ArticleAnnals of surgical oncology2018
Sarcopenia and Comorbidity in Gastric Cancer Surgery as a Useful Combined Factor to Predict Eventual Death from Other Causes.
Article in Annals of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04306562 (Effect of Oral Protein Supplementation on Postoperative Complications in Elderly Sarcopenic Cancerous Patients), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Oral Protein Supplementation on Postoperative Complications in Elderly Sarcopenic Cancerous Patients: A Randomized Controlled Trial
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Low skeletal muscle mass and postoperative morbidity in surgical oncology: a systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Body composition assessment and sarcopenia in patients with gastric cancer: a systematic review and meta-analysis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019Pooled it
- Sex Differences in the Association Between Low Skeletal Muscle Mass and Overall Survival in Patients With Gastric Cancer After Gastrectomy: A Retrospective Cohort Study.World journal of surgery · 2026Article
- Effect of total gastrectomy on weight and body composition: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Impact of the Cachexia Index on survival and recurrence in patients undergoing surgery for gastric cancer.Surgery today · 2026Article
- Effect of Preoperative Sarcopenic Obesity on Outcomes in Patients with Gastric Cancer After Surgery.Cancers · 2026Article
- Article
- Prognostic significance and model evaluation of the modified advanced lung cancer inflammation index in locally advanced resectable gastric cancer patients with neoadjuvant chemotherapy.Frontiers in oncology · 2026Article
- Computed tomography defined body composition may predict postoperative outcomes and prognosis following gastric cancer surgery.Turkish journal of surgery · 2025Article
- Article
- Impact of infectious complications after gastrectomy on non‑gastric cancer‑related deaths.Oncology letters · 2024Article
- Lifestyle Behaviors in Patients With Gastric Cancer: Continuous Need for Alcohol Abstinence and Muscle Strength Training Education.Journal of gastric cancer · 2024Article
- Impact of malnutrition and nutritional support after gastrectomy in patients with gastric cancer.Annals of gastroenterological surgery · 2024Review
- Is sarcopenia effective on survival in patients with metastatic gastric cancer?World journal of gastrointestinal oncology · 2024Article
- Association Between Body Composition and Survival in Patients With Gastroesophageal Adenocarcinoma: An Automated Deep Learning Approach.JCO clinical cancer informatics · 2024Article
- A comprehensive study on non-cancer-related mortality risk factors in elderly gastric cancer patients post-curative surgery.BMC gastroenterology · 2024Article
- Article
- Prevalence and associations of sarcopenia, obesity and sarcopenic obesity in end-stage knee osteoarthritis patients.Journal of health, population, and nutrition · 2023Article
- Gastric Cancer with Sarcopenia: an Area Worth Focusing On.Current treatment options in oncology · 2023Review
- Sarcopenia of kidney transplant recipients as a predictive marker for reduced graft function and graft survival after kidney transplantation.Langenbeck's archives of surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSarcopenia is recognized as an important prognostic factor in various types of cancer, including gastric cancer. While long-term survival analyses typically focus on overall and disease-specific survival, death from other causes has received far less attention.
methodsWe reviewed medical records of 491 gastric cancer patients who underwent gastrectomy from January 2005 to March 2014 and whose preoperative computed tomography (CT) images were available for evaluation of sarcopenia. Sarcopenia was defined as the SMA/BSA index (skeletal muscle area divided by body surface area) below the sex-specific lowest quartile.
resultsSarcopenia was significantly associated with age, high body mass index (BMI), presence of comorbidity, high American Society of Anesthesiologists physical status (ASA-PS), high T score, advanced stage, large blood loss, and long hospital stay, but was not significantly associated with postoperative complications. Univariate and multivariate analyses of prognostic factors for overall survival revealed that sarcopenia is an independent predictor of poor prognosis [hazard ratio (HR) 1.46, 95% confidence interval (CI) 1.01-2.09, p = 0.0454]. Our analysis of death due to other causes found that non-gastric cancer-related deaths were more frequent among sarcopenia patients with comorbidities than in the rest of our study population (p = 0.0001), while univariate and multivariate analyses revealed that sarcopenia with comorbidity was an independent risk factor for non-gastric cancer-related death (HR 1.84, 95% CI 1.31-3.61, p = 0.0308), as was age.
conclusionFor gastric cancer patients, sarcopenia increases the risk of death from other causes following surgery, which reveals the importance of developing treatment strategies based not only on cancer status but also on other clinical factors, including sarcopenia and comorbidity.
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