Evidence map›Paper›PMID 29404773›Full record

ArticleEuropean radiology2018

Dual-energy CT: a phantom comparison of different platforms for abdominal imaging.

Thorsten Sellerer, Peter B Noël, Manuel Patino, Anushri Parakh, Sebastian Ehn, Sascha Zeiter, Jasmin A Holz, Johannes Hammel, Alexander A Fingerle, Franz Pfeiffer and 4 more

Abstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

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  10. Advanced X-Ray Imaging Technology.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thorsten SellererChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany. thorsten.sellerer@tum.de.
Peter B NoëlChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany.
Manuel PatinoDivision of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Anushri ParakhDivision of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Sebastian EhnChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany.
Sascha ZeiterInstitute of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.
Jasmin A HolzInstitute of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.
Johannes HammelChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany.
Alexander A FingerleChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany.
Franz PfeifferChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany.
David MaintzInstitute of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.
Ernst J RummenyDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Daniela MuenzelChair for Biomedical Physics, Department of Physics and Munich School of BioEngineering, Technical University of Munich, James-Franck-Str. 1, 85748, Garching, Germany.
Dushyant V SahaniDivision of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.

Funding

Bundesministerium für Bildung und Forschung 13GW0072C
6 · The paper itself

Abstract

objectivesEvaluation of imaging performance across dual-energy CT (DECT) platforms, including dual-layer CT (DLCT), rapid-kVp-switching CT (KVSCT) and dual-source CT (DSCT).

methodsA semi-anthropomorphic abdomen phantom was imaged on these DECT systems. Scans were repeated three times for CTDIvol levels of 10 mGy, 20 mGy, 30 mGy and different fat-simulating extension rings. Over the available range of virtual-monoenergetic images (VMI), noise as well as quantitative accuracy of hounsfield units (HU) and iodine concentrations were evaluated.

resultsFor all VMI levels, HU values could be determined with high accuracy compared to theoretical values. For KVSCT and DSCT, a noise increase was observed towards lower VMI levels. A patient-size dependent increase in the uncertainty of quantitative iodine concentrations is observed for all platforms. For a medium patient size the iodine concentration root-mean-square deviation at 20 mGy is 0.17 mg/ml (DLCT), 0.30 mg/ml (KVSCT) and 0.77mg/ml (DSCT).

conclusionNoticeable performance differences are observed between investigated DECT systems. Iodine concentrations and VMI HUs are accurately determined across all DECT systems. KVSCT and DLCT deliver slightly more accurate iodine concentration values than DSCT for investigated scenarios. In DLCT, low-noise and high-image contrast at low VMI levels may help to increase diagnostic information in abdominal CT. KEY POINTS: • Current dual-energy CT platforms provide accurate, reliable quantitative information. • Dual-energy CT cross-platform evaluation revealed noticeable performance differences between different systems. • Dual-layer CT offers constant noise levels over the complete energy range.

Indexed as

Phantoms, ImagingAbdomenAnthropometryEquipment DesignHumansIodineRadiography, AbdominalRadiography, Dual-Energy Scanned ProjectionTomography, X-Ray ComputedIodineComparative studyComputed tomography, X-rayIodineQuantitative evaluationRadiologic phantom

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.