Evidence map›Paper›PMID 29404767›Full record

ArticleEuropean radiology2018

Shear-wave elastography can evaluate annulus fibrosus alteration in adolescent scoliosis.

Tristan Langlais, Claudio Vergari, Raphael Pietton, Jean Dubousset, Wafa Skalli, Raphael Vialle

Abstract readEvaluation Study
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Assessment of malalignment at early stage in adolescent idiopathic scoliosis: a longitudinal cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  9. Evidence of spinal stiffening following fusionless bipolar fixation for neuromuscular scoliosis: a shear wave elastography assessment of lumbar annulus fibrosus.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Review
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  11. Ultrasound Elastography in Children.Children (Basel, Switzerland) · 2023
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  15. Comparison of annulus fibrosus cell collagen remodeling rates in a microtissue system.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tristan LanglaisDepartment for Innovative Therapies in Musculoskeletal Diseases, DHU MAMUTH - Department of Pediatric Orthopaedic, Armand Trousseau Hospital, Université Pierre et Marie Curie Paris 6 - 26 avenue du Dr Arnold Netter, 75571, Paris Cedex 12, France. tristanlanglais@yahoo.fr.ORCID http://orcid.org/0000-0003-1427-5518
Claudio VergariArts et Metiers ParisTech, LBM/Institut de Biomécanique Humaine Georges Charpak, 151 boulevard de l'hôpital, 75013, Paris, France.
Raphael PiettonDepartment for Innovative Therapies in Musculoskeletal Diseases, DHU MAMUTH - Department of Pediatric Orthopaedic, Armand Trousseau Hospital, Université Pierre et Marie Curie Paris 6 - 26 avenue du Dr Arnold Netter, 75571, Paris Cedex 12, France.
Jean DuboussetArts et Metiers ParisTech, LBM/Institut de Biomécanique Humaine Georges Charpak, 151 boulevard de l'hôpital, 75013, Paris, France.
Wafa SkalliArts et Metiers ParisTech, LBM/Institut de Biomécanique Humaine Georges Charpak, 151 boulevard de l'hôpital, 75013, Paris, France.
Raphael VialleDepartment for Innovative Therapies in Musculoskeletal Diseases, DHU MAMUTH - Department of Pediatric Orthopaedic, Armand Trousseau Hospital, Université Pierre et Marie Curie Paris 6 - 26 avenue du Dr Arnold Netter, 75571, Paris Cedex 12, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn vitro studies showed that annulus fibrosus lose its integrity in idiopathic scoliosis. Shear-wave ultrasound elastography can be used for non-invasive measurement of shear-wave speed (SWS) in vivo in the annulus fibrosus, a parameter related to its mechanical properties. The main aim was to assess SWS in lumbar annulus fibrosus of scoliotic adolescents and compare it to healthy subjects.

methodsSWS was measured in 180 lumbar IVDs (L3L4, L4L5, L5S1) of 30 healthy adolescents (13 ± 1.9 years old) and 30 adolescent idiopathic scoliosis patients (13 ± 2 years old, Cobb angle: 28.8° ± 10.4°). SWS was compared between the scoliosis and healthy control groups.

resultsIn healthy subjects, average SWS (all disc levels pooled) was 3.0 ± 0.3 m/s, whereas in scoliotic patients it was significantly higher at 3.5 ± 0.3 m/s (p = 0.0004; Mann-Whitney test). Differences were also significant at all disc levels. No difference was observed between males and females. No correlation was found with age, weight and height.

conclusionNon-invasive shear-wave ultrasound is a novel method of assessment to quantitative alteration of annulus fibrosus. These preliminary results are promising for considering shear-wave elastography as a biomechanical marker for assessment of idiopathic scoliosis. KEY POINTS: • Adolescent idiopathic scoliosis may have an altered lumbar annulus fibrosus. • Shear-wave elastography can quantify lumbar annulus fibrosus mechanical properties. • Shear-wave speed was higher in scoliotic annulus than in healthy subjects. • Elastography showed potential as a biomechanical marker for characterizing disc alteration.

Indexed as

AdolescentAnnulus FibrosusChildElasticity Imaging TechniquesFemaleHealthy VolunteersHumansLumbosacral RegionMaleScoliosisAnnulus fibrosusElasticity imaging techniquesPaediatricsScoliosisSpine

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.