ReviewDer Anaesthesist2018
[Hypovolemic and hemorrhagic shock].
Review in Der Anaesthesist, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Inhospital coagulation management and fluid replacement therapy in patients with multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Pooled it
- Beyond Paradox: Ozone Therapy as a Hormetic Modulator in Ischemia-Reperfusion Injury - An Update.Cell biochemistry and biophysics · 2025Review
- Polymicrobial Infection (Gram-Positive and Gram-Negative) Exacerbates Systemic Inflammatory Response Syndrome in a Conscious Swine Extremity Trauma Model.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Article
- Does the Injection Site Matter During CPR? A Systematic Review and Meta-Analysis of Drug Pharmacokinetics and Pharmacodynamics.Journal of clinical medicine · 2025Review
- MicroRNA-451: A multifaceted regulator in cerebral and cardiac ischemia-reperfusion injury - from molecular mechanisms to therapeutic potential.Molecular biology reports · 2025Review
- Lactylation: a promising therapeutic target in ischemia-reperfusion injury management.Cell death discovery · 2025Review
- Understanding the complex role of exosomes in intestinal ischemia-reperfusion injury: from pathogenesis to protection.Frontiers in pharmacology · 2025Review
- Photodynamic therapy of severe hemorrhagic shock on yolk-shell MoSRSC advances · 2024Article
- Rational Design and Testing of Antibacterial Aloe Vera Hemostatic Hydrogel.Gels (Basel, Switzerland) · 2024Article
- [The chapters "Stop the bleed-prehospital" and "Coagulation management and volume therapy (emergency departement)" in the new S3 guideline "Polytrauma/severe injury treatment"].Notfall & rettungsmedizin · 2023Review
- [Tourniquet use in the Helicopter Emergency Medical Service : Analysis based on data of the DRF Luftrettung (German Air Rescue) in the period 2015-2020].Der Anaesthesist · 2022Article
- Effect of Transradial Artery Catheterization on Shock Patients.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Emergency Blood Transfusion for Trauma and Perioperative Resuscitation: Standard of Care.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021Review
- Bioelectric, tissue, and molecular characteristics of the gastric mucosa at different times of ischemia.Experimental biology and medicine (Maywood, N.J.) · 2021Article
- The order of vasopressor discontinuation and incidence of hypotension: a retrospective cohort analysis.Scientific reports · 2021Article
- Effect of types of placenta previa on maternal and neonatal outcomes: a 10-year retrospective cohort study.Archives of gynecology and obstetrics · 2021Article
- A Portable Biodevice to Monitor Salivary Conductivity for the Rapid Assessment of Fluid Status.Journal of personalized medicine · 2021Article
- Revised Injury Severity Classification II (RISC II) is a predictor of mortality in REBOA-managed severe trauma patients.PloS one · 2021Article
- [Lactate in emergency medicine].Der Anaesthesist · 2020Review
- [36-years-old male following motorcycle accident with high velocity trauma : Preparation for the medical specialist examination: part 34].Der Anaesthesist · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term "shock" refers to a life-threatening circulatory failure caused by an imbalance between the supply and demand of cellular oxygen. Hypovolemic shock is characterized by a reduction of intravascular volume and a subsequent reduction in preload. The body compensates the loss of volume by increasing the stroke volume, heart frequency, oxygen extraction rate, and later by an increased concentration of 2,3-diphosphoglycerate with a rightward shift of the oxygen dissociation curve. Hypovolemic hemorrhagic shock impairs the macrocirculation and microcirculation and therefore affects many organ systems (e.g. kidneys, endocrine system and endothelium). For further identification of a state of shock caused by bleeding, vital functions, coagulation tests and hematopoietic procedures are implemented. Every hospital should be in possession of a specific protocol for massive transfusions. The differentiated systemic treatment of bleeding consists of maintenance of an adequate homeostasis and the administration of blood products and coagulation factors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.