Evidence map›Paper›PMID 29404544›Full record

ArticleThe Analyst2018

Selecting optimal features from Fourier transform infrared spectroscopy for discrete-frequency imaging.

Rupali Mankar, Michael J Walsh, Rohit Bhargava, Saurabh Prasad, David Mayerich

Abstract read
In one paragraph

Article in The Analyst, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rupali MankarDepartment of Electrical and Computer Engineering, University of Houston, Houston, TX, USA. mayerich@uh.edu.
Michael J Walsh
Rohit Bhargava
Saurabh Prasad
David Mayerich

Funding

Discrete Frequency Infrared Spectroscopic Imaging for Breast HistopathologyR01EB009745 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT · 2010 to 2025
$5.1M
Large-Scale Reconstruction of Microvascular Networks and the Surrounding CellularR00LM011390 · NLM · UNIVERSITY OF HOUSTON · PI MAYERICH, DAVID · 2014 to 2016
$730k
Early detection of diabetic nephropathy in kidney transplants by chemical imaging approachesR21DK103066 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WALSH, MICHAEL JOHN · 2015 to 2016
$426k
NIBIB NIH HHS R01 EB009745NIDDK NIH HHS R21 DK103066NLM NIH HHS R00 LM011390
6 · The paper itself

Abstract

Tissue histology utilizing chemical and immunohistochemical labels plays an important role in biomedicine and disease diagnosis. Recent research suggests that mid-infrared (IR) spectroscopic imaging may augment histology by providing quantitative molecular information. One of the major barriers to this approach is long acquisition time using Fourier-transform infrared (FTIR) spectroscopy. Recent advances in discrete frequency sources, particularly quantum cascade lasers (QCLs), may mitigate this problem by allowing selective sampling of the absorption spectrum. However, DFIR imaging only provides a significant advantage when the number of spectral samples is minimized, requiring a priori knowledge of important spectral features. In this paper, we demonstrate the use of a GPU-based genetic algorithm (GA) using linear discriminant analysis (LDA) for DFIR feature selection. Our proposed method relies on pre-acquired broadband FTIR images for feature selection. Based on user-selected criteria for classification accuracy, our algorithm provides a minimal set of features that can be used with DFIR in a time-frame more practical for clinical diagnosis.

Identifiers

PMID29404544
PMCPMC5860915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.