Evidence map›Paper›PMID 29404451›Full record

ArticleHepatology communications2017

MicroRNA therapy inhibits hepatoblastoma growth

Emilie Indersie, Sarah Lesjean, Katarzyna B Hooks, Francis Sagliocco, Tony Ernault, Stefano Cairo, Maria Merched-Sauvage, Anne Rullier, Brigitte Le Bail, Sophie Taque and 8 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Wnt/β-Catenin Signaling in Liver Pathobiology.Annual review of pathology · 2025
    Review
  6. Review
  7. Article
  8. DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  9. Review
  10. Article
  11. Porphyran fromMarine drugs · 2023
    Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Emilie IndersieUniv. Bordeaux, Inserm, GREF, U1053, 33076 Bordeaux France.
Sarah LesjeanUniv. Bordeaux, Inserm, GREF, U1053, 33076 Bordeaux France.
Katarzyna B HooksUniv. Bordeaux, Inserm, GREF, U1053, 33076 Bordeaux France.ORCID 0000-0003-0687-4393
Francis SaglioccoUniv. Bordeaux, Inserm, GREF, U1053, 33076 Bordeaux France.
Tony ErnaultINSERM, UMR 1193, Paul-Brousse Hospital, Hepatobiliary Centre F-94800 Villejuif France.
Stefano CairoXenTechEvry France.
Maria Merched-SauvageBordeaux University Hospital Bordeaux France.
Anne RullierBordeaux University Hospital Bordeaux France.
Brigitte Le BailBordeaux University Hospital Bordeaux France.
Sophie TaqueRennes University Hospital Rennes France.
Michael GrotzerSIOPEL (International Childhood Liver Tumours Strategy Group) Liver Tumor and Tissue Banking Program University Children's Hospital Zürich Switzerland.
Sophie BranchereauBicêtre Hospital Le Kremlin-Bicêtre France.
Catherine GuettierBicêtre Hospital Le Kremlin-Bicêtre France.
Monique FabreNecker Hospital Paris France.
Laurence BrugièresGustave Roussy Cancer Campus Villejuif France.
Martin HagedornUniv. Bordeaux, Inserm, GREF, U1053, 33076 Bordeaux France.
Marie-Annick BuendiaINSERM, UMR 1193, Paul-Brousse Hospital, Hepatobiliary Centre F-94800 Villejuif France.
Christophe F GrossetUniv. Bordeaux, Inserm, GREF, U1053, 33076 Bordeaux France.
Université de Bordeaux · FRBordeaux Population Health · FRInserm · FRCentre Hospitalier Universitaire de Rennes · FRHôpital Necker-Enfants Malades · FRUniversity Children's Hospital Zurich · CHUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatoblastoma (HBL) is the most common pediatric liver cancer. In this malignant neoplasm, beta-catenin protein accumulates and increases Wnt signaling due to recurrent activating mutations in the catenin-beta 1 (

Identifiers

PMID29404451
PMCPMC5721429
OpenAlexW2604757458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.