Evidence map›Paper›PMID 29404418›Full record

ArticlemSphere

Intravaginal Administration of Interleukin 12 during Genital Gonococcal Infection in Mice Induces Immunity to Heterologous Strains of

Yingru Liu, Julianny Perez, Laura A Hammer, Heather C Gallagher, Magdia De Jesus, Nejat K Egilmez, Michael W Russell

Open access · goldAbstract read
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Article
  3. Frontiers in microbiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Unveiling the immune dynamics ofInfection and immunity · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Immune responses toFrontiers in immunology · 2023
    Review
  14. Recent Progress Towards a Gonococcal Vaccine.Frontiers in cellular and infection microbiology · 2022
    Review
  15. Editorial: PathogenicFrontiers in cellular and infection microbiology · 2022
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Yingru LiuTherapyX, Inc., Buffalo, New York, USA.
Julianny PerezTherapyX, Inc., Buffalo, New York, USA.
Laura A HammerTherapyX, Inc., Buffalo, New York, USA.
Heather C GallagherDepartment of Biomedical Sciences, University at Albany, Albany, New York, USA.
Magdia De JesusDepartment of Biomedical Sciences, University at Albany, Albany, New York, USA.
Nejat K EgilmezTherapyX, Inc., Buffalo, New York, USA.
Michael W RussellDepartment of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA.
Therapyx (United States) · USNew York State Department of Health · USUniversity at Albany, State University of New York · USUniversity at Buffalo, State University of New York · USUniversity of Louisville · US

Funding

Therapy and Prophylaxis for Genital Tract InfectionR44AI104067 · NIAID · THERAPYX, INC. · PI AUCI, DOMINICK, RUSSELL, MICHAEL W · 2014 to 2022
$4.4M
Therapy and Prophylaxis for Genital Tract InfectionSB1AI104067 · NIAID · THERAPYX, INC. · PI AUCI, DOMINICK, RUSSELL, MICHAEL W · 2023 to 2025
$3.0M
Therapy and Prophylaxis for Genital Tract InfectionR43AI104067 · NIAID · THERAPYX, INC. · PI LIU, YINGRU · 2013 to 2013
$300k
NIAID NIH HHS R43 AI104067NIAID NIH HHS R44 AI104067NIAID NIH HHS SB1 AI104067
6 · The paper itself

Abstract

It has previously been shown that genital tract infection with

Indexed as

adaptive immunitygenital tract immunityinterleukin 12microencapsulationNeisseria gonorrhoeae

Identifiers

PMID29404418
PMCPMC5793040
OpenAlexW2789897879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.