Evidence map›Paper›PMID 29404364›Full record

ArticleAnnals of translational medicine2018

Peri-procedural antibiotic prophylaxis in ventricular septal defect: a case study to re-visit guidelines.

Nadish Garg, Mannu Nayyar, Rami N Khouzam, Salem A Salem, Devarshi Ardeshna

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nadish GargDepartment of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Mannu NayyarDepartment of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Rami N KhouzamDepartment of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Salem A SalemDepartment of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Devarshi ArdeshnaMedical Student, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
University of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current American Heart Association (AHA)/American College of Cardiology (ACC) guidelines do not recommend antibiotic prophylaxis for infective endocarditis (IE) in patients with acyanotic congenital valvular heart disease due to lack of any proven benefit and potential harm associated with antibiotics. As recognized by the guidelines, some acyanotic congenital heart disease, such as ventricular septal defects (VSDs), are associated with a high velocity jet and pose a greater risk of peri-procedural endocarditis. We suggest that an acyanotic congenital heart disease with high velocity jet should be considered for antibiotic prophylaxis for IE.

Indexed as

antibiotic prophylaxisinfective endocarditis (IE)Ventricular septal defect (VSD)

Identifiers

PMID29404364
PMCPMC5787728
OpenAlexW2772579988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.