ArticleTurkish thoracic journal2015
Mediastinal Teratoma with Coexisting Adenocarcinoma and Carcinoid Tumor (Somatic-Type Malignancy): A Case Report with a Review of the Literature.
Article in Turkish thoracic journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 15 citations in OpenAlex.
- Mediastinal Mature Teratoma With Malignant Transformation to Colorectal-Type Adenocarcinoma.Annals of thoracic surgery short reports · 2026Article
- Arising Mediastinal Adenocarcinoma in A Patient With A 14 Years History of Mature Teratoma.Respirology case reports · 2025Article
- A neuroendocrine tumor within an anterior mediastinal mature teratoma: a case report.Journal of cardiothoracic surgery · 2022Article
- Unusual giant multilocular thymic cyst with mature teratoma including a carcinoid component in the mediastinum.Surgical case reports · 2022Article
- Adenocarcinoma and neuroendocrine tumor arising within presacral teratoma associated with Currarino syndrome: A case report.The Indian journal of radiology & imagingArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
Germ cell tumors constitute 10% to 15% of anterior mediastinal neoplasms. Of these, mature teratoma is the most common. Somatic malignant transformation in mature teratoma is a very rare phenomenon. In the anterior mediastinum, few cases of malignant transformation in the form of carcinoma, sarcoma, or neuroendocrine tumors have been described. We present the case of a mature mediastinal teratoma in a 24-year-old female, diagnosed on computed tomography, where both carcinoid tumor and adenocarcinoma were seen. To the best of our knowledge, this is the first report of such a case. Malignant transformation in a mature teratoma confers a significantly worse prognosis and is difficult to diagnose only on clinical and radiological evaluation. As these lesions are so rare, the treatment options for these lesions are also not clearly defined. Extensive sampling and careful microscopic examination are needed when teratomas are submitted for pathological evaluation.
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