ArticleJournal of pharmaceutical analysis2016
The impact of storage conditions upon gentamicin coated antimicrobial implants.
Article in Journal of pharmaceutical analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Wear-resistant antibacterial UHMWPE-based implant materials obtained by radiation crosslinking.Biomaterials science · 2025Article
- Effect of tropical climates on the quality of commonly used antibiotics: the protocol for a systematic review and meta-analysis.BMJ open · 2025Article
- Large-Scale Development of Antibacterial Scaffolds: Gentamicin Sulfate-Loaded Biodegradable Nanofibers for Gastrointestinal Applications.ACS omega · 2023Article
- Highly Adhesive Antimicrobial Coatings for External Fixation Devices.Gels (Basel, Switzerland) · 2023Article
- Thermophilic Exopolysaccharide Films: A Potential Device for Local Antibiotic Delivery.Pharmaceutics · 2023Article
- Antibiotics- and Heavy Metals-Based Titanium Alloy Surface Modifications for Local Prosthetic Joint Infections.Antibiotics (Basel, Switzerland) · 2021Review
- Long-term stability of gentamicin sulfate-ethylenediaminetetraacetic acid disodium salt (EDTA-NaJournal of pharmaceutical analysis · 2018Article
- Antibiotic release from F-doped nanotubular oxide layer on TI6AL4V alloy to decrease bacterial viability.Journal of materials science. Materials in medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A systematic approach was developed to investigate the stability of gentamicin sulfate (GS) and GS/poly (lactic-co-glycolic acid) (PLGA) coatings on hydroxyapatite surfaces. The influence of environmental factors (light, humidity, oxidation and heat) upon degradation of the drug in the coatings was investigated using liquid chromatography with evaporative light scattering detection and mass spectrometry. GS coated rods were found to be stable across the range of environments assessed, with only an oxidizing atmosphere resulting in significant changes to the gentamicin composition. In contrast, rods coated with GS/PLGA were more sensitive to storage conditions with compositional changes being detected after storage at 60 °C, 75% relative humidity or exposure to light. The effect of γ-irradiation on the coated rods was also investigated and found to have no significant effect. Finally, liquid chromatography-mass spectrometry analysis revealed that known gentamines C
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.