Evidence map›Paper›PMID 29404002›Full record

ArticleJournal of pharmaceutical analysis2016

Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine.

Patitapabana Parida, Subash Chandra Mishra, Subhashree Sahoo, Ajit Behera, Bibhukalyan Prasad Nayak

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patitapabana ParidaDepartment of Biotechnology and Medical Engineering, NIT Rourkela, Odisha 769008, India.
Subash Chandra MishraDepartment of Metallurgical and Materials Engineering, NIT Rourkela, Odisha 769008, India.
Subhashree SahooDepartment of Pharmaceutics, Kanakmanjari Institute of Pharmaceutical Sciences, Rourkela, Odisha 769015, India.
Ajit BeheraDepartment of Metallurgical and Materials Engineering, IIT Kharagpur, West Bengal 721302, India.
Bibhukalyan Prasad NayakDepartment of Biotechnology and Medical Engineering, NIT Rourkela, Odisha 769008, India.
National Institute of Technology Rourkela · INIndian Institute of Technology Kharagpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article introduced the work of ethylcellulose based polymeric microsphere loaded with nifedipine for reduction in frequency of administration with low solubility in aqueous medium and high rate of absorption in the stomach. The non-aqueous polymeric suspension was put dropwise into an aqueous medium containing polyvinyl alcohol as a surfactant for the synthesis of microsphere by solvent evaporation. The microspheres were characterized by different techniques, namely, XRD, SEM, and NMR. The formation of microspheres was confirmed by SEM. XRD analysis revealed the semi-crystallinity nature of microspheres. The NMR study indicated the presence of hetero-aromatic nucleus in the microsphere.

Indexed as

MicrosphereNifedipineSolvent evaporationSustained release

Identifiers

PMID29404002
PMCPMC5762602
OpenAlexW2062704265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.