Evidence map›Paper›PMID 29403967›Full record

ArticleJournal of pharmaceutical analysis2016

Determination of lercanidipine in human plasma by an improved UPLC-MS/MS method for a bioequivalence study.

Darshan V Chaudhary, Daxesh P Patel, Priyanka A Shah, Jaivik V Shah, Mallika Sanyal, Pranav S Shrivastav

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  4. Exploring DrugCentral: from molecular structures to clinical effects.Journal of computer-aided molecular design · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Darshan V ChaudharyDepartment of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, Gujarat 380009, India.
Daxesh P PatelLaboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD 20892, USA.
Priyanka A ShahDepartment of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, Gujarat 380009, India.
Jaivik V ShahDepartment of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, Gujarat 380009, India.
Mallika SanyalDepartment of Chemistry, St. Xavier's College, Navrangpura, Ahmedabad, Gujarat 380009, India.
Pranav S ShrivastavDepartment of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, Gujarat 380009, India.
Gujarat University · INCenter for Cancer Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An improved and reliable ultra-performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method has been developed and validated for the determination of lercanidipine in human plasma. Plasma samples with lercanidipine-d3 as an internal standard (IS) were prepared by solid phase extraction on Phenomenex Strata-X cartridges using 100 µL of human plasma. Chromatographic analysis was performed on UPLC BEH C

Indexed as

BioequivalenceHuman plasmaLercanidipineSolid phase extractionUPLC–MS/MS

Identifiers

PMID29403967
PMCPMC5762449
OpenAlexW1778745885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.