Evidence map›Paper›PMID 29403827›Full record

ArticleJournal of pharmaceutical analysis2013

Application of UPLC-MS/MS for separation and quantification of 3α-Hydroxy Tibolone and comparative bioavailability of two Tibolone formulations in healthy volunteers.

Vijay P Shinde, Ashutosh Pudage, Arvind Jangid, Hiren Mistri, P K Patel

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vijay P ShindeKadi Sarva Vishvavidyalaya, Sarva Vidyalaya Campus, Sector 15/23, Gandhinagar, India.
Ashutosh PudageAccutest Research Laboratories (I) Pvt. Ltd., Unit II, Opp. The Grand Bhagwati Hotel, S.G. Highway, Bodakdev, Ahmedabad 380059, India.
Arvind JangidAccutest Research Laboratories (I) Pvt. Ltd., Unit II, Opp. The Grand Bhagwati Hotel, S.G. Highway, Bodakdev, Ahmedabad 380059, India.
Hiren MistriAccutest Research Laboratories (I) Pvt. Ltd., Unit II, Opp. The Grand Bhagwati Hotel, S.G. Highway, Bodakdev, Ahmedabad 380059, India.
P K PatelKadi Sarva Vishvavidyalaya, Sarva Vidyalaya Campus, Sector 15/23, Gandhinagar, India.
Physical Research Laboratory · INKadi Sarva Vishwavidyalaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel, fast, sensitive and robust method based on ultra-performance liquid chromatography coupled to atmospheric pressure electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) has been developed to separate two Tibolone stereoisomers i.e., 3α-Hydroxy Tibolone and 3β-Hydroxy Tibolone and to quantify 3α-Hydroxy Tibolone using p-toulenesulfonyl isocyanate (PTSI) as a derivatizing reagent in human plasma. 3α-Hydroxy Tibolone-

Indexed as

Pharmacokineticsp-toulenesulfonyl isocyanateTiboloneUPLC

Identifiers

PMID29403827
PMCPMC5760983
OpenAlexW2069270521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.