ArticleFrontiers in immunology2018
Incomplete Memories: The Natural Suppression of Tissue-Resident Memory CD8 T Cells in the Lung.
Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Regulation of respiratory CD8+ T-cell immunity by suppressive monocyte-like dendritic cells (MCs).Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Allergic airway recall responses require IL-9 from resident memory CD4Science immunology · 2022Article
- Tissue resident memory T cells in the respiratory tract.Mucosal immunology · 2022Review
- Monocyte-Derived Dendritic Cells (moDCs) Differentiate into Bcl6Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Engineering Vaccines for Tissue-Resident Memory T Cells.Advanced therapeutics · 2021Article
- Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections.Frontiers in immunology · 2021Review
- Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals.Frontiers in immunology · 2021Article
- Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection.The Journal of experimental medicine · 2020Article
- Legend of the Sentinels: Development of Lung Resident Memory T Cells and Their Roles in Diseases.Frontiers in immunology · 2020Review
- Tissue-Resident Memory T Cells in Mice and Humans: Towards a Quantitative Ecology.Journal of immunology (Baltimore, Md. : 1950) · 2019Review
- PD-1Science immunology · 2019Article
- Th2-TFrontiers in immunology · 2019Article
- Establishment and Maintenance of Conventional and Circulation-Driven Lung-Resident Memory CD8Frontiers in immunology · 2019Article
- Resident-Memory T Cells in Tissue-Restricted Immune Responses: For Better or Worse?Frontiers in immunology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The yearly, cyclic impact of viruses like influenza on human health and the economy is due to the high rates of mutation of traditional antibody targets, which negate any preexisting humoral immunity. However, the seasonality of influenza infections can equally be attributed to an absent or defective memory CD8 T cell response since the epitopes recognized by these cells are derived from essential virus proteins that mutate infrequently. Experiments in mouse models show that protection from heterologous influenza infection is temporally limited and conferred by a population of tissue-resident memory (T
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.