ArticleFrontiers in pharmacology2018
Differential Contribution of Constituent Metal Ions to the Cytotoxic Effects of Fast-Dissolving Metal-Oxide Nanoparticles.
Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Impact of particle size and surface modifications on the neurotoxic potential of copper oxide nanoparticles.Scientific reports · 2025Article
- Article
- Toxicity of Metal Oxide Nanoparticles: Looking through the Lens of Toxicogenomics.International journal of molecular sciences · 2023Article
- Article
- A New Look at the Effects of Engineered ZnO and TiONanomaterials (Basel, Switzerland) · 2022Review
- Bioactive properties of ZnO nanoparticles synthesized using3 Biotech · 2022Article
- Non-antimicrobial and Non-anticancer Properties of ZnO Nanoparticles Biosynthesized Using Different Plant Parts ofACS omega · 2022Article
- Skin Sensitization Potential and Cellular ROS-Induced Cytotoxicity of Silica Nanoparticles.Nanomaterials (Basel, Switzerland) · 2021Article
- Evaluation of the skin sensitization potential of metal oxide nanoparticles using the ARE-Nrf2 Luciferase KeratinoSensToxicological research · 2021Article
- Dual Ion Releasing Nanoparticles for Modulating Osteogenic Cellular Microenvironment of Human Mesenchymal Stem Cells.Materials (Basel, Switzerland) · 2021Article
- Copper and Cobalt Ions Released from Metal Oxide Nanoparticles Trigger Skin Sensitization.Frontiers in pharmacology · 2021Article
- Prediction of Skin Sensitization Potential of Silver and Zinc Oxide Nanoparticles Through the Human Cell Line Activation Test.Frontiers in toxicology · 2021Article
- Evaluation of the Skin Sensitization Potential of Carbon Nanotubes Using Alternative In Vitro and In Vivo Assays.Toxics · 2020Article
- Iron-Doping of Copper Oxide Nanoparticles Lowers Their Toxic Potential on C6 Glioma Cells.Neurochemical research · 2020Article
- Article
- The Use of Nanomedicine for Targeted Therapy against Bacterial Infections.Antibiotics (Basel, Switzerland) · 2019Review
- Metal Oxide Nanoparticles in Therapeutic Regulation of Macrophage Functions.Nanomaterials (Basel, Switzerland) · 2019Review
- Uptake of Intact Copper Oxide Nanoparticles Causes Acute Toxicity in Cultured Glial Cells.Neurochemical research · 2019Article
- Grouping of Poorly Soluble Low (Cyto)Toxic Particles: Example with 15 Selected Nanoparticles and A549 Human Lung Cells.Nanomaterials (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main mechanism of toxicity for fast-dissolving nanoparticles (NPs) is relatively simple as it originates from the intrinsic toxicity of their constituent elements rather than complicated surface reactivity. However, there is little information about the compared toxicity of fast-dissolving NP and its constituent ion, which is essential for understanding the mechanism of NP toxicity and the development of a structure-toxicity relationship (STR) model. Herein, we selected three types of fast-dissolving metal-oxide NPs (CoO, CuO, and ZnO) and constituent metal chlorides (CoCl
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.