Evidence map›Paper›PMID 29403376›Full record

ArticleFrontiers in pharmacology2017

Chamaejasmine B Induces the Anergy of Vascular Endothelial Cells to VEGFA Pro-angiogenic Signal by Autophagic Regulation of VEGFR2 in Breast Cancer.

Qi Li, Xiaoxi Kan, Jie Yin, Lidong Sun, Yajie Wang, Yujie Li, Qing Yang, Hongbin Xiao, Ying Chen, Xiaogang Weng and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Effect of Babao Dan on angiogenesis of gastric cancerTranslational cancer research · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Qi LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaoxi KanInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Jie YinInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Lidong SunInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yajie WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yujie LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Qing YangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Hongbin XiaoKey Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Ying ChenInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaogang WengInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Weiyan CaiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaoxin ZhuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNCapital Medical University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neovascularization functions essentially for malignant upgrading and predicts poor prognosis in multiple cancers, which make it the highly effective strategy for clinical treatment. Unfortunately, the known anti-angiogenic therapies show low effectiveness against breast cancer. Recently, rebalancing the pro-angiogenic property in microenvironment shows great advantages and attracts increasing attention for breast cancer treatment. Herein, we for the first time reported that Chamaejasmine B (ICJ), extracted from

Indexed as

anti-angiogenesis chemotherapyautophagybreast cancerChamaejasmine BVEGFR2

Identifiers

PMID29403376
PMCPMC5786572
OpenAlexW2789175155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.