ArticleFrontiers in neuroanatomy2017
Hypothalamic Projections to the Optic Tectum in Larval Zebrafish.
Article in Frontiers in neuroanatomy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Histo-anatomical atlas of Garra rufa and its thermal tolerance at human body temperature.Scientific reports · 2026Article
- The tectal melanocortin system modulates energy-dependent visual avoidance behavior in zebrafish.iScience · 2026Article
- On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025Review
- Eat, flee, freeze: Division of labor in the larval zebrafish visuomotor system.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- RFC2 may contribute to the pathogenicity of Williams syndrome revealed in a zebrafish model.Journal of genetics and genomics = Yi chuan xue bao · 2024Article
- CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression.Biomolecules · 2024Article
- A synaptic corollary discharge signal suppresses midbrain visual processing during saccade-like locomotion.Nature communications · 2023Article
- From perception to behavior: The neural circuits underlying prey hunting in larval zebrafish.Frontiers in neural circuits · 2023Review
- Deficiency in the cell-adhesion moleculeFrontiers in cell and developmental biology · 2023Article
- The Superior Colliculus: Cell Types, Connectivity, and Behavior.Neuroscience bulletin · 2022Review
- Time-Dependent Monitoring of Dopamine in the Brain of Live Embryonic Zebrafish Using Electrochemically Pretreated Carbon Fiber Microelectrodes.ACS measurement science au · 2022Article
- Single-Cell RNA Sequencing Characterizes the Molecular Heterogeneity of the Larval Zebrafish Optic Tectum.Frontiers in molecular neuroscience · 2022Article
- The tectum/superior colliculus as the vertebrate solution for spatial sensory integration and action.Current biology : CB · 2021Review
- Contributions of Luminance and Motion to Visual Escape and Habituation in Larval Zebrafish.Frontiers in neural circuits · 2021Article
- Pyramidal Neurons of the Zebrafish Tectum Receive Highly Convergent Input From Torus Longitudinalis.Frontiers in neuroanatomy · 2021Article
- Neuromodulation and Behavioral Flexibility in Larval Zebrafish: From Neurotransmitters to Circuits.Frontiers in molecular neuroscience · 2021Article
- Identification of GABAergic neurons innervating the zebrafish lateral habenula.The European journal of neuroscience · 2020Article
- Article
- Anatomy and Connectivity of the Torus Longitudinalis of the Adult Zebrafish.Frontiers in neural circuits · 2020Article
- The Mormyrid Optic Tectum Is a Topographic Interface for Active Electrolocation and Visual Sensing.Frontiers in neuroanatomy · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The optic tectum of larval zebrafish is an important model for understanding visual processing in vertebrates. The tectum has been traditionally viewed as dominantly visual, with a majority of studies focusing on the processes by which tectal circuits receive and process retinally-derived visual information. Recently, a handful of studies have shown a much more complex role for the optic tectum in larval zebrafish, and anatomical and functional data from these studies suggest that this role extends beyond the visual system, and beyond the processing of exclusively retinal inputs. Consistent with this evolving view of the tectum, we have used a Gal4 enhancer trap line to identify direct projections from rostral hypothalamus (RH) to the tectal neuropil of larval zebrafish. These projections ramify within the deepest laminae of the tectal neuropil, the stratum album centrale (SAC)/stratum griseum periventriculare (SPV), and also innervate strata distinct from those innervated by retinal projections. Using optogenetic stimulation of the hypothalamic projection neurons paired with calcium imaging in the tectum, we find rebound firing in tectal neurons consistent with hypothalamic inhibitory input. Our results suggest that tectal processing in larval zebrafish is modulated by hypothalamic inhibitory inputs to the deep tectal neuropil.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.