Evidence map›Paper›PMID 29403348›Full record

ArticleFrontiers in neuroscience2018

Training for Micrographia Alters Neural Connectivity in Parkinson's Disease.

Evelien Nackaerts, Jochen Michely, Elke Heremans, Stephan P Swinnen, Bouwien C M Smits-Engelsman, Wim Vandenberghe, Christian Grefkes, Alice Nieuwboer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
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  4. Rehabilitative interventions for impaired handwriting in people with Parkinson's disease: a scoping review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
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  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Evelien NackaertsDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Jochen MichelyDepartment of Neurology, Cologne University Hospital, Cologne, Germany.
Elke HeremansDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Stephan P SwinnenDepartment of Movement Sciences, KU Leuven, Leuven, Belgium.
Bouwien C M Smits-EngelsmanDepartment of Health and Rehabilitation Sciences, University of Cape Town, Cape Town, South Africa.
Wim VandenbergheDepartment of Neurology, University Hospitals Leuven, Leuven, Belgium.
Christian GrefkesDepartment of Neurology, Cologne University Hospital, Cologne, Germany.
Alice NieuwboerDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
KU Leuven · BEUniversity Hospital Cologne · DEUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in clarifying the neural networks underlying rehabilitation in Parkinson's disease (PD), the impact of prolonged motor learning interventions on brain connectivity in people with PD is currently unknown. Therefore, the objective of this study was to compare cortical network changes after 6 weeks of visually cued handwriting training (= experimental) with a placebo intervention to address micrographia, a common problem in PD. Twenty seven early Parkinson's patients on dopaminergic medication performed a pre-writing task in both the presence and absence of visual cues during behavioral tests and during fMRI. Subsequently, patients were randomized to the experimental (

Indexed as

dynamic causal modelingmicrographiamotor learningParkinson's diseasevisual cueing

Identifiers

PMID29403348
PMCPMC5780425
OpenAlexW2788751660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.