ArticleInfection and drug resistance2018
Timing of antibiotic administration and lactate measurement in septic shock patients: a comparison between hospital wards and the emergency department.
Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Association of Time of Day with Delays in Antimicrobial Initiation among Ward Patients with Hospital-Onset Sepsis.Annals of the American Thoracic Society · 2023Article
- Comparison of Race-Based and Non-Race-Based Equations for Kidney Function Estimation in Critically Ill Thai Patients for Vancomycin Dosing.Journal of clinical pharmacology · 2022Article
- Association of Unit Census with Delays in Antimicrobial Initiation among Ward Patients with Hospital-acquired Sepsis.Annals of the American Thoracic Society · 2022Article
- An approach to antibiotic treatment in patients with sepsis.Journal of thoracic disease · 2020Review
- Antimicrobials administration time in patients with suspected sepsis: is faster better? An analysis by propensity score.Journal of intensive care · 2020Article
- Presenting Symptoms in Sepsis: Is the Mnemonic "SEPSIS" Useful?Infection and drug resistance · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe timing of intravenous antibiotic administration and lactate measurement is associated with survival of septic shock patients. Septic shock patients were admitted to the medical intensive care unit (MICU) from 2 major sources: hospital ward and emergency department (ED). This study aimed to compare the timing of antibiotic administration and lactate measurement between hospital wards and the ED. PATIENTS AND
methodsMedical data were collected from adult patients admitted to the MICU with septic shock from January 2015 to December 2016. "Time Zero" was defined as the time of diagnosis of sepsis. The associations between the times and risk-adjusted 28-day mortality were assessed.
resultsIn total, 150 septic shock patients were admitted to the MICU. The median time interval (hour [h] interquartile range [IQR]) from time zero to antibiotic administration was higher in patients from the hospital wards compared to those from the ED (4.84 [3.5-8.11] vs 2.04 [1.37-3.54],
conclusionAntibiotic administration in septic shock patients from the hospital wards took longer, and there was also less appropriate antibiotic prescriptions seen in this group compared with those admitted from the ED. However, neither the timing of antibiotic administration nor lactate measurement was associated with mortality.
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