Evidence map›Paper›PMID 29403264›Full record

ArticleDrug design, development and therapy2018

Anticonvulsant and reproductive toxicological studies of the imidazole-based histamine H3R antagonist

Salim M Bastaki, Yousef M Abdulrazzaq, Mohamed Shafiullah, Małgorzata Więcek, Katarzyna Kieć-Kononowicz, Bassem Sadek

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Multi-Targeting Ligand ST-2223 with Histamine HInternational journal of molecular sciences · 2021
    Article
  6. The Dual-Active Histamine HInternational journal of molecular sciences · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Salim M BastakiDepartment of Pharmacology and Therapeutics, College of Medicine and Health Science, United Arab Emirates University, Al Ain.
Yousef M AbdulrazzaqDepartment of Medical Education, Dubai Health Authority, Dubai, UAE.
Mohamed ShafiullahDepartment of Pharmacology and Therapeutics, College of Medicine and Health Science, United Arab Emirates University, Al Ain.
Małgorzata WięcekDepartment of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna, Kraków, Poland.
Katarzyna Kieć-KononowiczDepartment of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna, Kraków, Poland.
Bassem SadekDepartment of Pharmacology and Therapeutics, College of Medicine and Health Science, United Arab Emirates University, Al Ain.
Jagiellonian University · PLUnited Arab Emirates University · AEDubai Health Authority · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The imidazole-based H3R antagonist

Indexed as

Abnormalities, Drug-InducedAnimalsAnticonvulsantsBody WeightDose-Response Relationship, DrugFemaleFetusHistamine H3 AntagonistsImidazolesMaleMethylhistaminesMiceOrganogenesisPlacentaPregnancyTeratogensalpha-methylhistamineAnticonvulsantsHistamine H3 Antagonistshistamine H3R antagonist 2-18ImidazolesMethylhistaminesTeratogensValproic AcidanticonvulsantgestationH3R receptor antagonistmalformationmaximal electroshockmice

Identifiers

PMID29403264
PMCPMC5783147
OpenAlexW2783908515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.