Evidence map›Paper›PMID 29402947›Full record

ArticleScientific reports2018

Intracellular calcium signal at the leading edge regulates mesodermal sheet migration during Xenopus gastrulation.

Kentaro Hayashi, Takamasa S Yamamoto, Naoto Ueno

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Leveraging CRISPR-Cas13d in an inducible knockdown system to interrogatebioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The Organizer and Its Signaling in Embryonic Development.Journal of developmental biology · 2021
    Review
  12. Review
  13. Review
  14. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  15. Recent advances in bioelectronics chemistry.Chemical Society reviews · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Connexins in Astrocyte Migration.Frontiers in pharmacology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kentaro HayashiDepartment of Developmental Biology, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki, Aichi, 444-8585, Japan.
Takamasa S YamamotoDepartment of Developmental Biology, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki, Aichi, 444-8585, Japan.
Naoto UenoDepartment of Developmental Biology, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki, Aichi, 444-8585, Japan. nueno@nibb.ac.jp.ORCID http://orcid.org/0000-0002-8375-2317
National Institute for Basic Biology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the gastrulation stage in animal embryogenesis, the cells leading the axial mesoderm migrate toward the anterior side of the embryo, vigorously extending cell protrusions such as lamellipodia. It is thought that the leading cells sense gradients of chemoattractants emanating from the ectodermal cells and translate them to initiate and maintain the cell movements necessary for gastrulation. However, it is unclear how the extracellular information is converted to the intracellular chemical reactions that lead to motion. Here we demonstrated that intracellular Ca

Indexed as

Calcium SignalingAnimalsCalciumCalcium IonophoresCell MovementChelating AgentsEctodermEgtazic AcidEmbryo, NonmammalianGastrulaGastrulationGene ExpressionIonomycinMesodermPseudopodiarac1 GTP-Binding Protein1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl esterCalciumCalcium IonophoresChelating AgentsEgtazic AcidIonomycinrac1 GTP-Binding Protein

Identifiers

PMID29402947
PMCPMC5799360
OpenAlexW2807388156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.