SynthesisCerebrovascular diseases extra2018
Oral Health and Brain Injury: Causal or Casual Relation?
Synthesis in Cerebrovascular diseases extra, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05549648 (Artificial Intelligence-Based APP for Home Oral Muscles Exercises for Healthy Adults), which is not on this map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Artificial Intelligence-Based APP for Home Oral Muscles Exercises for Healthy Adults
Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Evidence-Based Mouth and Oral Health Individualised Treatment Plan in Adults With Acquired Brain Injury: A Cluster Nonrandomized Controlled Trial.Journal of oral rehabilitation · 2026Trial
- Article
- Oral health and its association with dysphagia severity and nutritional vulnerability after stroke: a structural equation modeling study.Clinical oral investigations · 2026Article
- Reduced Posterior Occlusal Contacts Are Associated With an Increased Risk of Stroke: A Retrospective Study Based on a Japanese Claims Database.Journal of the American Heart Association · 2026Article
- Oral frailty trajectories and influencing factors in older adults with stroke: a longitudinal study.BMC nursing · 2025Article
- Disparities in periodontitis risk and healthcare use among individuals with disabilities in Korea: a retrospective cohort study.BMC oral health · 2025Article
- Oral Microbiome Dysbiosis as a Risk Factor for Stroke: A Comprehensive Review.Microorganisms · 2024Review
- Understanding Emergency Room Visits for Nontraumatic Oral Health Conditions in a Hospital Serving Rural Appalachia: Dental Informatics Study.JMIR formative research · 2022Article
- The Link between Stroke Risk and Orodental Status-A Comprehensive Review.Journal of clinical medicine · 2022Review
- Oral health status and its associated factors among post-stroke inpatients: a cross-sectional study in Hungary.BMC oral health · 2022Article
- Effect of Morbidities, Depression, Anxiety, and Stress on Oral Health-Related Quality of Life among Migrant Elderly Following Children in Weifang, China.International journal of environmental research and public health · 2022Article
- Best Practice Recommendations for Dysphagia Management in Stroke Patients: A Consensus from a Portuguese Expert Panel.Portuguese journal of public health · 2022Article
- Dental Care Use, Edentulism, and Systemic Health among Older Adults.Journal of dental research · 2021Article
- Evaluation of Oral Hygiene Status in Patients with Hemorrhagic and Ischemic Stroke.Journal of pharmacy & bioallied sciences · 2021Article
- Structural Equation Modeling of Tongue Function and Tongue Hygiene in Acute Stroke Patients.International journal of environmental research and public health · 2021Article
- Oral Health Status in Older People with Dementia: A Case-Control Study.Journal of clinical medicine · 2021Article
- Effectiveness of Standard Oral Care Plan During Hospital Stay in Individuals With Brain Injury.Frontiers in neurology · 2021Article
- Microglial response to experimental periodontitis in a murine model of Alzheimer's disease.Scientific reports · 2020Article
- Effect of Mucosal Brushing on the Serum Levels of C-Reactive Protein for Patients Hospitalized with Acute Symptoms.Medicina (Kaunas, Lithuania) · 2020Article
- Gender Differences in the Levels of Periodontal Destruction, Behavioral Risk Factors and Systemic Oxidative Stress in Ischemic Stroke Patients: A Cohort Pilot Study.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo systematically review the current literature investigating the association between oral health and acquired brain injury.
methodsA structured search strategy was applied to PubMed, Embase, Web of Science, and CENTRAL electronic databases until March 2017 by 2 independent reviewers. The preferred reporting items for systematic review and meta-analysis guidelines were used for systematic review.
resultsEven though the objective was to assess the association between oral health and acquired brain injury, eligible studies focused solely on different forms of stroke and stroke subtypes. Stroke prediction was associated with various factors such as number of teeth, periodontal conditions (even after controlling for confounding factors), clinical attachment loss, antibody levels to Aggregatibacter actinomycetemcomitans and Prevotella intermedia. The literature showed no consensus on the possible association between gingivitis and stroke. Patients with stroke generally had poorer oral hygiene practices and oral health. Dental prophylaxis and professional intervention reduced the incidence of stroke.
conclusionsOverall, oral health and stroke were related. Periodontitis and tooth loss were independently associated with stroke. However, prevention and timely intervention may reduce the risk of stroke. Stroke was the main cerebral lesion studied in the literature, with almost no publications on other brain lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.