Evidence map›Paper›PMID 29402285›Full record

ArticleJournal of neuroinflammation2018

Sara Belloli, Lucia Zanotti, Valentina Murtaj, Cristina Mazzon, Giuseppe Di Grigoli, Cristina Monterisi, Valeria Masiello, Leonardo Iaccarino, Andrea Cappelli, Pietro Luigi Poliani and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroinflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. TSPO Radioligands for Neuroinflammation: An Overview.Molecules (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Contribution of Intravital Neuroimaging to Study Animal Models of Multiple Sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. TSPO imaging in animal models of brain diseases.European journal of nuclear medicine and molecular imaging · 2021
    Review
  13. Article
  14. Article
  15. In vivo imaging of CNS microglial activation/macrophage infiltration with combined [European journal of nuclear medicine and molecular imaging · 2021
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Sara BelloliIBFM-CNR, Segrate, Italy.
Lucia ZanottiUnit of Immunogenetics, Leukemia Genomics and Immunobiology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Valentina MurtajExperimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Cristina MazzonHumanitas Clinical and Research Centre, Rozzano, Italy.
Giuseppe Di GrigoliIBFM-CNR, Segrate, Italy.
Cristina MonterisiDepartment of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, Monza, 20900, Italy.
Valeria MasielloDepartment of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, Monza, 20900, Italy.
Leonardo IaccarinoVita-Salute San Raffaele University and In Vivo Human Molecular and Structural Neuroimaging Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Andrea CappelliDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Pietro Luigi PolianiDepartment of Molecular and Translational Medicine, Pathology Unit, University of Brescia, Brescia, Italy.
Letterio Salvatore PolitiExperimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Rosa Maria MorescoIBFM-CNR, Segrate, Italy. moresco.rosamaria@hsr.it.
University of Milano-Bicocca · ITVita-Salute San Raffaele University · ITBoston Children's Hospital · USIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleUniversity of Brescia · ITUniversity of Padua · ITUniversity of Siena · IT

Funding

Cluster Tecnologico Nazionale Scienze della Vita ALISEI - MIUR CTN01_00177_165430FP7-HEALTH-2011-INNOVATION-1 HEALTH-F2-2011-278850
6 · The paper itself

Abstract

backgroundPositron emission tomography (PET) using translocator protein (TSPO) ligands has been used to detect neuroinflammatory processes in neurological disorders, including multiple sclerosis (MS). The aim of this study was to evaluate neuroinflammation in a mouse MS model (EAE) using TSPO-PET with

methodsMOG

resultsIn vivo and ex vivo analyses show that

conclusionIncrease of

Indexed as

Amino Acid SequenceAnimalsDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalFemaleFluorine RadioisotopesMagnetic Resonance ImagingMiceMice, Inbred C57BLMultiple SclerosisPositron-Emission TomographyQuinolinesFluorine-18Fluorine RadioisotopesQuinolinesVC701 compoundEAE monophasic modelMRIMultiple sclerosisNeuroinflammationTSPO-PET

Identifiers

PMID29402285
PMCPMC5800080
OpenAlexW2788884364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.