Evidence map›Paper›PMID 29402233›Full record

Observational studyBMC cardiovascular disorders2018

A population-based screening study for cardiovascular diseases and diabetes in Danish postmenopausal women: acceptability and prevalence.

Marie Dahl, Lars Frost, Rikke Søgaard, Ib Christian Klausen, Vibeke Lorentzen, Jes Lindholt

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Involving people with type 2 diabetes in facilitating participation in a cardiovascular screening programme.Health expectations : an international journal of public participation in health care and health policy · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Abdominal aortic aneurysms.Nature reviews. Disease primers · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marie DahlCardiovascular Research Centre, Regional Hospital Central Denmark, Heibergs Allé 4, 8800, Viborg, Denmark. marie.dahl@rm.dk.ORCID 0000-0003-3814-1709
Lars FrostCardiovascular Research Centre, Regional Hospital Central Denmark, Heibergs Allé 4, 8800, Viborg, Denmark.
Rikke SøgaardDepartment of Public Health and Department of Clinical Medicine, Aarhus University, 8000, Aarhus, Denmark.
Ib Christian KlausenCardiovascular Research Centre, Regional Hospital Central Denmark, Heibergs Allé 4, 8800, Viborg, Denmark.
Vibeke LorentzenCardiovascular Research Centre, Regional Hospital Central Denmark, Heibergs Allé 4, 8800, Viborg, Denmark.
Jes LindholtCardiovascular Research Centre, Regional Hospital Central Denmark, Heibergs Allé 4, 8800, Viborg, Denmark.
Regional Hospital Central Jutland · DKAarhus University · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReducing women's cardiovascular risk and the economic costs associated with cardiovascular diseases (CVD) and diabetes (DM) continues to be a challenge. Whether a multifaceted CVD screening programme is beneficial as a preventive strategy in women remains uncertain. The aim of this study was to investigate the prevalence of CVD and DM as well as the acceptability toward screening and preventive actions.

methodsAn observational study was performed among all women born in 1936, 1941, 1946 and 1951 living in Viborg Municipality, Denmark, from October 2011. In total, 1984 were invited to screening for abdominal aortic aneurysm (AAA), peripheral arterial disease (PAD), carotid plaque (CP), hypertension (HT), atrial fibrillation (AF), DM and dyslipidaemia. Participants with positive tests were offered prophylactic intervention including follow-up consultations in case of AAA, PAD and/or CP. Participants with AAA ≥ 50 mm were referred to specialists in vascular surgery. Women with AF or potential familial hypercholesterolaemia (FH) were referred to cardiology work-up.

resultsAmong those invited, 1474 (74.3%) attended screening, but the attendees' share decreased with increasing age groups (p < 0.001). AAA was diagnosed in 10 (0.7%) women, PAD in 101 (6.9%) and CP in 602 (40.8%). The percentage of women with these conditions rose with increasing age group (p < 0.05). Unconfirmed potential HT was observed in 94 (6.4%), unknown AF in 6 (0.4%), DM in 14 (1%) and potential FH in 35 (2.4%). None of these findings differed across age groups. Among the 631 women diagnosed with AAA, PAD and/or CP, 182 (28.8%) were already in antiplatelet and 223 (35.3%) in lipid-lowering therapy prior to screening. Antiplatelet therapy was initiated in 215 (34.1%) and lipid-lowering therapy in 191 (30.3%) women. Initiation of antiplatelet and lipid-lowering therapy was further recommended to 134 (21.2%) and 141 (22.4%) women, respectively, who hesitated to follow the recommendation.

conclusionsThe study recorded an acceptable total attendance rate, even though a significantly lower attendance rate was observed in the eldest women. The identified hesitation towards prophylactic therapy may affect the rationale and effectiveness of CVD screening, and hesitation seems a critical issue that should be addressed in the design of future screening programmes.

Indexed as

Patient Acceptance of Health CarePostmenopauseAgedAge FactorsCardiovascular DiseasesDenmarkDiabetes MellitusFemaleHumansMass ScreeningMiddle AgedPredictive Value of TestsPrevalencePrognosisProgram EvaluationReferral and ConsultationAbdominal aortic aneurysmAtrial fibrillationCarotid plaqueDiabetes mellitus type 2HypertensionObservational studyPeripheral arterial diseasesScreening

Identifiers

PMID29402233
PMCPMC5800093
OpenAlexW2787169205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.