Evidence map›Paper›PMID 29402219›Full record

ArticleBMC cancer2018

Clinical characteristics of distal gastric cancer in young adults from Northeastern Brazil.

Manuel B Braga-Neto, Jessica Gomes Carneiro, Alzira M de Castro Barbosa, Igor S Silva, Danielle C Maia, Felipe S Maciel, Rafael Jorge Alves de Alcântara, Paulo Roberto L Vasconscelos, Lucia L B C Braga

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
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  5. Krukenberg Tumors: Does Surgical Resection Improve Survival?Indian journal of surgical oncology · 2025
    Article
  6. Article
  7. Surgical treatment of gastric adenocarcinoma: what factors influence the prognosis?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025
    Observational
  8. Efficacy and safety of chemotherapy in young patients with advanced gastroesophageal adenocarcinoma: data from the Spanish AGAMENON-SEOM registry.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
    Article
  9. Review
  10. Article
  11. Temporal trends and spatial clusters of gastric cancer mortality in Brazil.Revista panamericana de salud publica = Pan American journal of public health · 2022
    Article
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  13. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Manuel B Braga-NetoDepartment of Internal Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
Jessica Gomes CarneiroClinical Research Unit, Federal University of Ceará, Fortaleza, CE, Brazil.
Alzira M de Castro BarbosaHospital Universitário Walter Cantídio, Federal University of Ceará, Fortaleza, CE, Brazil.
Igor S SilvaClinical Research Unit, Federal University of Ceará, Fortaleza, CE, Brazil.
Danielle C MaiaHospital Universitário Walter Cantídio, Federal University of Ceará, Fortaleza, CE, Brazil.
Felipe S MacielClinical Research Unit, Federal University of Ceará, Fortaleza, CE, Brazil.
Rafael Jorge Alves de AlcântaraClinical Research Unit, Federal University of Ceará, Fortaleza, CE, Brazil.
Paulo Roberto L VasconscelosDepartment of Surgery, Federal University of Ceará, Fortaleza, CE, Brazil.
Lucia L B C BragaDepartment of Internal Medicine, Federal University of Ceará, Fortaleza, CE, Brazil. lucialib@terra.com.br.
Universidade Federal do Ceará · BR

Funding

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico 135067154
6 · The paper itself

Abstract

backgroundIt has been suggested that distal gastric carcinoma (GC) in younger patients has a more aggressive outcome than in older patients, however this is a controversial issue. The aim of this study was to compare clinicopathological features between younger and older patients with GC in Northeastern Brazil.

methodsA total of 207 patients with distal GC (41 patients ≤45 years, considered younger group, and 166 > 45 years, considered older group) were evaluated prospectively during a 6 year period.

resultsThe mean patient age in the young group was 37.41 years old and 64.43 years in the older group. No significant difference was found regarding gender, area of residence, history of alcohol consumption, chronic tobacco smoking. Prevalence of first-degree GC history was 12.5% (7.3% in younger group vs. 13.9% in older; p <  0.46). The most frequent symptom was gastric pain and weight loss. Diffuse infiltrative cancer was more frequently seen in younger patients (70.70% vs. 33.70%, respectively; p <  0.01), as was histologically less differentiated tumors (63.40% vs. 33.10%; p <  0.01) and stage IV of GC (48.80% vs. 30.70%; p <  0.015). Five-year survival, evaluated in 82 patients, was lower in younger patients (p = 0.045); however, after adjusting for stage of GC in the multivariate analysis, this association did not remain significant. Family history of GC and gender had no impact on survival.

conclusionsYounger patients showed higher prevalence of diffuse type of Lauren and lower survival that was attributed to higher rate of advanced stage of GC. Gastric cancer screening strategies should also be considered in younger individuals, especially in areas of high prevalence. Further studies are warranted to determine risk factors associated with gastric cancer in young adults.

Indexed as

AdultAgedAged, 80 and overAge FactorsBrazilFemaleHumansMaleMiddle AgedNeoplasm StagingProspective StudiesRisk AssessmentRisk FactorsStomach NeoplasmsSurvival AnalysisYoung AdultBrazilDistal gastric cancerRisk factorsYoung adults

Identifiers

PMID29402219
PMCPMC5800037
OpenAlexW2795447838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.