ArticleBMC infectious diseases2018
Diabetes and the occurrence of infection in primary care: a matched cohort study.
Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Five comparative cohorts to assess the risk of genital tract infections associated with sodium-glucose cotransporter-2 inhibitors initiation in type 2 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association · 2022Pooled it
- Wilderness Medical Society Clinical Practice Guidelines for Diabetes Management.Wilderness & environmental medicine · 2019Guideline
- Type 2 Diabetes: How Much of an Autoimmune Disease?Frontiers in endocrinology · 2019Pooled it
- Incidence of skin and soft tissue infections in general practice and out-of-hours services in Norway 2006-2022.Scandinavian journal of primary health care · 2026Article
- NLRP3 inflammasome partially mediates genotoxiciScience · 2026Article
- Predictive Value of the CURB-65, MuLBSTA, Pneumonia Severity Index Scores and Laboratory Parameters for In-Hospital Mortality in Patients with Diabetes Mellitus and COVID-19 Infection.Journal of clinical medicine · 2026Article
- Epidemiological profile and antimicrobial resistance of urinary tract infections in diabetic versus non-diabetic individuals.BMC infectious diseases · 2026Article
- Primary Pyomyositis of the Adductor and Pectineus Muscle in Patients With Uncontrolled Diabetes: Report of Two Cases.Case reports in orthopedics · 2026Article
- Live fast, die young: neutrophils streamline their metabolism to maximize inflammation.Infection and immunity · 2025Review
- 2025 Clinical Practice Guidelines for Diabetes Management in Korea: Recommendation of the Korean Diabetes Association.Diabetes & metabolism journal · 2025Article
- Blood glucose management in hospitalized patients: a review of current literature.Annals of medicine and surgery (2012) · 2025Review
- Availability and affordability of diabetes healthcare services associated with the frequency of diabetes-related complications.BMC health services research · 2024Article
- Ultrasound-Responsive HBD Peptide Hydrogel with Antibiofilm Capability for Fast Diabetic Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Longitudinal assessment of the impact of prevalent diabetes on hospital admissions and mortality in the general population: a prospective population-based study with 19 years of follow-up.BMC public health · 2024Article
- Type-2 diabetes mellitus enhancesbioRxiv : the preprint server for biology · 2024Article
- Comorbidities of chronic rhinosinusitis in children and adults.Clinical and translational allergy · 2024Article
- Association of Diabetes Mellitus With Increased Mortality in Carbapenem-Resistant Enterobacterales Infections.Cureus · 2024Article
- Incident infection risks depending on oral antidiabetic exposure in insulin-treated type 2 diabetes patients.Scientific reports · 2023Article
- Diabetes and infectious disease mortality in Mexico City.BMJ open diabetes research & care · 2023Article
- Does poverty increase antibiotic prescribing rates through underlying health conditions? Ecological study using parallel mediation analysis.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeople with diabetes may be at higher risk for acquiring infections through both glucose-dependent and biologic pathways independent of glycemic control. Our aim was to estimate the association between diabetes and infections occurring in primary care.
methodsUsing the Newfoundland and Labrador Sentinel of the Canadian Primary Care Sentinel Surveillance Network, patients with diabetes ≥18 years between 1 January 2008 and 31 March 2013 were included with at least 1-year of follow-up. We randomly matched each patient with diabetes on the date of study entry with up to 8 controls without diabetes. Primary outcome was the occurrence of ≥1 primary care physician visits for any infectious disease. Secondary outcomes included primary visits for head & neck, respiratory, gastrointestinal, genitourinary, skin and soft tissue, musculoskeletal, and viral infections. Using multivariable conditional logistic regression analysis, we measured the independent association between diabetes and the occurrence of infections.
resultsWe identified 1779 patients with diabetes who were matched to 11,066 patients without diabetes. Patients with diabetes were older, had a higher prevalence of comorbidities, and were more often referred to specialists. After adjusting for potential confounders, patients with diabetes had an increased risk of any infection compared to patients without diabetes (adjusted odds ratio = 1.21, 95% confidence interval 1.07-1.37). Skin and soft tissue infections had the strongest association, followed by genitourinary, gastrointestinal, and respiratory infections. Diabetes was not associated with head and neck, musculoskeletal, or viral infections.
conclusionPatients with diabetes appear to have an increased risk of certain infections compared to patients without diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.