Evidence map›Paper›PMID 29402129›Full record

ArticleFree radical research2018

Reduction kinetics and electrochemistry of tetracarboxylate nitroxides.

Shengdian Huang, Hui Zhang, Joseph T Paletta, Suchada Rajca, Andrzej Rajca

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Free radical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. ChemistryOpen · 2019
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shengdian Huanga Department of Chemistry , University of Nebraska , Lincoln , NE , USA.
Hui Zhanga Department of Chemistry , University of Nebraska , Lincoln , NE , USA.
Joseph T Palettaa Department of Chemistry , University of Nebraska , Lincoln , NE , USA.
Suchada Rajcaa Department of Chemistry , University of Nebraska , Lincoln , NE , USA.
Andrzej Rajcaa Department of Chemistry , University of Nebraska , Lincoln , NE , USA.

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI MCHAOURAB, HASSANE S · 2010 to 2017
$31.9M
New Nitroxide Spin Labels for Distance Measurements in Biological SystemsR01GM124310 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI RAJCA, ANDRZEJ · 2017 to 2020
$1.7M
Synthesis of Metal-Free Magnetic Resonance Imaging Contrast AgentsR01EB019950 · NIBIB · UNIVERSITY OF NEBRASKA LINCOLN · PI RAJCA, ANDRZEJ · 2015 to 2018
$1.2M
NIBIB NIH HHS R01 EB019950NIGMS NIH HHS R01 GM124310NIGMS NIH HHS U54 GM087519
6 · The paper itself

Abstract

Tetracarboxylate pyrroline nitroxides undergo very fast reduction with ascorbate/glutathione (GSH), with second-order rate constants that are five orders of magnitude greater than those for gem-diethyl pyrroline nitroxides. For tetracarboxylate nitroxides, the electrochemical reduction potentials, measured by square wave voltammetry, are much less negative (by about 0.8 V), compared with the corresponding gem-diethyl nitroxides, while the oxidation potentials become more positive (by about 0.7 V). Electrochemical potentials correlate well via simple regressions with field/inductive parameters such as Swain/Lupton F-parameters (and/or Charton σ

Indexed as

ElectrochemistryKineticsNitrogen OxidesSpin LabelsNitrogen OxidesSpin LabelsElectrochemistryelectron paramagnetic resonanceHammett correlationnitroxidevoltammetry

Identifiers

PMID29402129
PMCPMC5908753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.