Evidence map›Paper›PMID 29401683›Full record

ReviewInternational journal of molecular sciences2018

Epigenetics and MicroRNAs in Cancer.

Alice Ramassone, Sara Pagotto, Angelo Veronese, Rosa Visone

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. World journal of gastrointestinal oncology · 2025
    Article
  6. Article
  7. The DNA methylation landscape of musculoskeletal sarcomas.Exploration of targeted anti-tumor therapy · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Navigating the genomic instability mine field of osteosarcoma to better understand implications of non-coding RNAs.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alice RamassoneAgeing Research Center and Translational Medicine-CeSI-MeT, 66100 Chieti, Italy. alice.ramassone@unich.it.
Sara PagottoAgeing Research Center and Translational Medicine-CeSI-MeT, 66100 Chieti, Italy. sara.pagotto@unich.it.
Angelo VeroneseAgeing Research Center and Translational Medicine-CeSI-MeT, 66100 Chieti, Italy. a.veronese@unich.it.
Rosa VisoneAgeing Research Center and Translational Medicine-CeSI-MeT, 66100 Chieti, Italy. r.visone@unich.it.
University of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional structure of the genome is exploited by cancer cells to promote tumorigenesis. This reprogramming occurs because of hereditable chromatin chemical modifications and the consequent formation of RNA-protein-DNA complexes that represent the principal actors of the epigenetic phenomena. In this regard, the deregulation of a transcribed non-coding RNA may be both cause and consequence of a cancer-related epigenetic alteration. This review summarizes recent findings that implicate microRNAs in the aberrant epigenetic regulation of cancer cells.

Indexed as

Epigenesis, GeneticGene Expression Regulation, NeoplasticGenome, HumanCell Transformation, NeoplasticChromatinDNA (Cytosine-5-)-Methyltransferase 1DNA MethylationDNA, NeoplasmFeedback, PhysiologicalHistonesHumansMicroRNAsNeoplasm ProteinsNeoplasmsSignal TransductionChromatinDNA (Cytosine-5-)-Methyltransferase 1DNA, NeoplasmDNMT1 protein, humanHistonesMicroRNAsNeoplasm Proteinsepigeneticshuman cancermicroRNAs

Identifiers

PMID29401683
PMCPMC5855681
OpenAlexW2793081232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.