Evidence map›Paper›PMID 29401674›Full record

ArticleInternational journal of molecular sciences2018

Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.

Jingyu He, Jiafeng Li, Han Liu, Zichao Yang, Fenghua Zhou, Ting Wei, Yaqian Dong, Hongjiao Xue, Lan Tang, Menghua Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Lactic Acid Bacteria Metabolites Modulate Immune Response AgainstAnimals : an open access journal from MDPI · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Therapeutic potentials of iridoids derived from Rubiaceae against in vitro and in vivo inflammation: A scoping review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jingyu HeBioengineering Research Centre, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458, China. jy.he@giat.ac.cn.
Jiafeng LiBioengineering Research Centre, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458, China. jiafengli2018@gmail.com.
Han LiuGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. hanliuchn@outlook.com.
Zichao YangGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. zcyangchn@163.com.
Fenghua ZhouSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China. wendy515@fimmu.com.
Ting WeiBioengineering Research Centre, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458, China. ting.wei@siat.ac.cn.
Yaqian DongGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. yqdongchn@163.com.
Hongjiao XueGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. xuehongjiao@sina.com.
Lan TangGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. tl405@smu.edu.cn.
Menghua LiuGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. liumenghua@smu.edu.cn.
Southern Medical University · CNGuangzhou Institute of Advanced Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The iridoids of

Indexed as

AnimalsAnti-Inflammatory AgentsCell SurvivalCyclooxygenase 2DinoprostoneHedyotisI-kappa B KinaseInterleukin-6IridoidsJNK Mitogen-Activated Protein KinasesLipopolysaccharidesMiceMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Molecular Docking SimulationNF-kappa BAnti-Inflammatory AgentsCyclooxygenase 2DinoprostoneI-kappa B KinaseInterleukin-6interleukin-6, mouseIridoidsJNK Mitogen-Activated Protein KinasesLipopolysaccharidesMapk1 protein, mouseMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NF-kappa BNitric OxideNitric Oxide Synthase Type IINos2 protein, mousep38 Mitogen-Activated Protein KinasesPlant ExtractsPtgs2 protein, mouseTumor Necrosis Factor-alphaanti-inflammationmitogen-activated protein kinasenuclear transcription factor kappa-B alpahascandoside

Identifiers

PMID29401674
PMCPMC5855679
OpenAlexW2782555529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.