ArticlePLoS genetics2018
STERILE APETALA modulates the stability of a repressor protein complex to control organ size in Arabidopsis thaliana.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 60 citations in OpenAlex.
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- Dynamic Metabolome and Transcriptome Profiling Provide Molecular Insights into Floral Bud Differentiation inBiology · 2025Article
- Transcriptional corepressor OsTPR1 regulates tillering and lateral root development in rice.Scientific reports · 2025Article
- The PEAPOD repressor complex in Arabidopsis stomatal development.Frontiers in plant science · 2025Review
- The chromosome-level assembly of the wild diploid alfalfa genome provides insights into the full landscape of genomic variations between cultivated and wild alfalfa.Plant biotechnology journal · 2024Article
- Molecular tagging of seed size using MITE markers in an induced large seed mutant with higher cotyledon cell size in groundnut.3 Biotech · 2024Article
- Genome-wide analysis of KIX gene family for organ size regulation in soybean (Frontiers in plant science · 2023Article
- Natural variation of GhSI7 increases seed index in cotton.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- PEAPOD repressors modulate and coordinate developmental responses to light intensity in Arabidopsis.The New phytologist · 2022Article
- Transcriptome Analysis of Citrus Dwarfing Viroid Induced Dwarfing Phenotype of Sweet Orange on Trifoliate Orange Rootstock.Microorganisms · 2022Article
- The auxin-responsive transcription factor SlDOF9 regulates inflorescence and flower development in tomato.Nature plants · 2022Article
- SlKIX8 and SlKIX9 are negative regulators of leaf and fruit growth in tomato.Plant physiology · 2022Article
- Whole-genome resequencing identified QTLs, candidate genes and Kompetitive Allele-Specific PCR markers associated with the large fruit of Atlantic Giant (Frontiers in plant science · 2022Article
- Article
- Transcriptional Regulation of Pine Male and Female Cone Initiation and Development: Key Players Identified Through Comparative Transcriptomics.Frontiers in genetics · 2022Article
- Multi-Approach Analysis Reveals Local Adaptation in a Widespread Forest Tree of Reunion Island.Plant & cell physiology · 2021Article
- The F-box protein MIO1/SLB1 regulates organ size and leaf movement in Medicago truncatula.Journal of experimental botany · 2021Article
- A Systems Biology Approach to Identify Essential Epigenetic Regulators for Specific Biological Processes in Plants.Plants (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organ size control is of particular importance for developmental biology and agriculture, but the mechanisms underlying organ size regulation remain elusive in plants. Meristemoids, which possess stem cell-like properties, have been recognized to play important roles in leaf growth. We have recently reported that the Arabidopsis F-box protein STERILE APETALA (SAP)/SUPPRESSOR OF DA1 (SOD3) promotes meristemoid proliferation and regulates organ size by influencing the stability of the transcriptional regulators PEAPODs (PPDs). Here we demonstrate that KIX8 and KIX9, which function as adaptors for the corepressor TOPLESS and PPD, are novel substrates of SAP. SAP interacts with KIX8/9 and modulates their protein stability. Further results show that SAP acts in a common pathway with KIX8/9 and PPD to control organ growth by regulating meristemoid cell proliferation. Thus, these findings reveal a molecular mechanism by which SAP targets the KIX-PPD repressor complex for degradation to regulate meristemoid cell proliferation and organ size.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.