Evidence map›Paper›PMID 29401432›Full record

ArticleBiophysical journal2018

Dynamic and Irregular Distribution of RyR2 Clusters in the Periphery of Live Ventricular Myocytes.

Florian Hiess, Pascal Detampel, Carme Nolla-Colomer, Alex Vallmitjana, Anutosh Ganguly, Matthias Amrein, Henk E D J Ter Keurs, Raul Benítez, Leif Hove-Madsen, S R Wayne Chen

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. CaThe Journal of physiology · 2026
    Article
  2. Cardiac Cell Remodeling in Obesity and Diabetes.Handbook of experimental pharmacology · 2026
    Review
  3. Structural Integrity of RyR2 Clusters Controls Cardiac Calcium Leak.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Ryanodine receptor cluster size sets the tone in cerebral smooth muscle.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  17. Dynamic L-type CaBiochimica et biophysica acta. Molecular cell research · 2018
    Article
  18. Dyadic Plasticity in Cardiomyocytes.Frontiers in physiology · 2018
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Florian HiessLibin Cardiovascular Institute of Alberta, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Pascal DetampelDepartment of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Carme Nolla-ColomerAutomatic Control Department, Universitat Politècnica de Catalunya-Barcelona Tech, Barcelona, Spain.
Alex VallmitjanaAutomatic Control Department, Universitat Politècnica de Catalunya-Barcelona Tech, Barcelona, Spain.
Anutosh GangulyDepartment of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.
Matthias AmreinDepartment of Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada.
Henk E D J Ter KeursLibin Cardiovascular Institute of Alberta, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Raul BenítezAutomatic Control Department, Universitat Politècnica de Catalunya-Barcelona Tech, Barcelona, Spain.
Leif Hove-MadsenBiomedical Research Institute Barcelona CSIC-IIBB, Sant Pau, Hospital de Sant Pau, Barcelona, Spain.
S R Wayne ChenLibin Cardiovascular Institute of Alberta, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada. Electronic address: swchen@ucalgary.ca.
Universitat Politècnica de Catalunya · ESUniversity of Calgary · CALibin Cardiovascular Institute of Alberta · CAHospital de Sant Pau · ESUniversity of Basel · CH

Funding

CIHR
6 · The paper itself

Abstract

Cardiac ryanodine receptors (RyR2s) are Ca

Indexed as

AnimalsCalciumCell SurvivalHeart VentriclesMiceMyocytes, CardiacProtein TransportRyanodine Receptor Calcium Release ChannelCalciumryanodine receptor 2. mouseRyanodine Receptor Calcium Release Channel

Identifiers

PMID29401432
PMCPMC5984973
OpenAlexW2785004435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.