ArticlePlant & cell physiology2018
The β-Ketoacyl-CoA Synthase HvKCS1, Encoded by Cer-zh, Plays a Key Role in Synthesis of Barley Leaf Wax and Germination of Barley Powdery Mildew.
Article in Plant & cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 57 citations in OpenAlex.
- Barley HvBODYGUARD1 controls cuticular specialisations regulated by SHINE transcription factors.The New phytologist · 2026Article
- Genome-wide analysis of KCS gene family in sunflower reveals the involvement of HaKCS1-1 in wax biosynthesis and drought resistance.BMC plant biology · 2026Article
- Article
- Identification of Leaf Waxy Candidate Gene and Expression Changes in Related Genes in Response to Cold Stress of Cabbage (Current issues in molecular biology · 2026Article
- Genome-wide characterization of the Eceriferum (CER) gene family in barley (Hordeum vulgare L.).Scientific reports · 2025Article
- Genome-Wide Identification of β-Ketoacyl CoA Synthase Gene Family in Melon (Current issues in molecular biology · 2025Article
- Shedding New Light on the Hull-Pericarp Adhesion Mechanisms of Barley Grains by Transcriptomics Analysis of IsogenicInternational journal of molecular sciences · 2024Article
- A GDSL-motif Esterase/Lipase Affects Wax and Cutin Deposition and Controls Hull-Caryopsis Attachment in Barley.Plant & cell physiology · 2024Article
- Gas Chromatography-Mass Spectrometry Metabolite Analysis Combined with Transcriptomics Reveals Genes Involved in Wax Biosynthesis inInternational journal of molecular sciences · 2024Article
- Snowball: a novel gene family required for developmental patterning of fruiting bodies of mushroom-forming fungi (Agaricomycetes).mSystems · 2024Article
- Beyond skin-deep: targeting the plant surface for crop improvement.Journal of experimental botany · 2023Review
- Transcription Factor TaMYB30 Activates Wheat Wax Biosynthesis.International journal of molecular sciences · 2023Article
- Genome-Wide Investigation and Functional Analysis Reveal ThatFoods (Basel, Switzerland) · 2023Article
- WAX INDUCER 1 Regulates β-Diketone Biosynthesis by Mediating Expression of theInternational journal of molecular sciences · 2023Article
- Germination Development of Powdery Mildew on Natural and Artificial Wheat Leaf Surfaces: A Study to Investigate Plant Wax Signals.Small science · 2023Article
- Genome-wide identification and expression analysis of 3-ketoacyl-CoA synthase gene family in rice (Frontiers in plant science · 2023Article
- Transcriptome Analysis Reveals a Comprehensive Virus Resistance Response Mechanism in Pecan Infected by a Novel Badnavirus Pecan Virus.International journal of molecular sciences · 2022Article
- Characterization of Glossy Spike Mutants and Identification of Candidate Genes Regulating Cuticular Wax Synthesis in Barley (International journal of molecular sciences · 2022Article
- Conserved signalling components coordinate epidermal patterning and cuticle deposition in barley.Nature communications · 2022Article
- Synthesis of CInternational journal of molecular sciences · 2022Review
Corrections and comments
- Erratum issuedErratum.2018
Authors and funding
13 authors at 8 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cuticle coats the primary aerial surfaces of land plants. It consists of cutin and waxes, which provide protection against desiccation, pathogens and herbivores. Acyl cuticular waxes are synthesized via elongase complexes that extend fatty acyl precursors up to 38 carbons for downstream modification pathways. The leaves of 21 barley eceriferum (cer) mutants appear to have less or no epicuticular wax crystals, making these mutants excellent tools for identifying elongase and modification pathway biosynthetic genes. Positional cloning of the gene mutated in cer-zh identified an elongase component, β-ketoacyl-CoA synthase (CER-ZH/HvKCS1) that is one of 34 homologous KCSs encoded by the barley genome. The biochemical function of CER-ZH was deduced from wax and cutin analyses and by heterologous expression in yeast. Combined, these experiments revealed that CER-ZH/HvKCS1 has a substrate specificity for C16-C20, especially unsaturated, acyl chains, thus playing a major role in total acyl chain elongation for wax biosynthesis. The contribution of CER-ZH to water barrier properties of the cuticle and its influence on the germination of barley powdery mildew fungus were also assessed.
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