Evidence map›Paper›PMID 29400443›Full record

ArticleACS chemical neuroscience2018

In Vivo Characterization of Two

Hui Liu, Hongjun Jin, Zonghua Luo, Xuyi Yue, Xiang Zhang, Hubert Flores, Yi Su, Joel S Perlmutter, Zhude Tu

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  2. Radiation dosimetry of [EJNMMI research · 2025
    Article
  3. Article
  4. Easily automated radiosynthesis of [Frontiers in bioengineering and biotechnology · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hui Liu
Hongjun Jin
Zonghua Luo
Xuyi Yue
Xiang Zhang
Hubert Flores
Yi Su
Joel S Perlmutter
Washington University in St. Louis · US

Funding

INVESTIGATIONS OF DEMENTIA IN PARKINSON DISEASER01NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2011 to 2021
$8.2M
PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
VALIDATION OF NEUROIMAGING BIOMARKERS FOR NIGROSTRIATAL NEURONSR01NS058714 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2008 to 2016
$4.4M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
Investigations of Dementia in Parkinson DiseaseRF1NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2023 to 2023
$2.3M
DEVELOPING PET AGENTS FOR IMAGING PHOSPHODIESTERASE 10A (PDE10A)R33MH092797 · NIMH · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2013 to 2015
$1.5M
DEVELOPMENT OF VESICULAR ACETYLCHOLINE TRANSPORTER IMAGING AGENTS FOR PETR21NS061025 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2009 to 2010
$628k
DEVELOPING PET AGENTS FOR IMAGING PHOSPHODIESTERASE 10A (PDE10A)R21MH092797 · NIMH · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2012
$530k
NCATS NIH HHS U54 TR001456NIMH NIH HHS R21 MH092797NIMH NIH HHS R33 MH092797NINDS NIH HHS R01 NS058714NINDS NIH HHS R01 NS075321NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R21 NS061025NINDS NIH HHS RF1 NS075321
6 · The paper itself

Abstract

Positron emission tomography (PET) with phosphodiesterase 10A (PDE10A) specific radioligands provides a noninvasive and quantitative imaging tool to access the expression of this enzyme in vivo under normal and diseased conditions. We recently reported two potent

Indexed as

Positron-Emission TomographyAnimalsBrainFluorine RadioisotopesImage Processing, Computer-AssistedNeostriatumPhosphodiesterase InhibitorsRadiopharmaceuticalsRatsTissue DistributionFluorine RadioisotopesPhosphodiesterase InhibitorsRadiopharmaceuticalsbrain imagingin vivo characterizationnonhuman primatesPET radioligandsPhosphodiesterase 10Apsychotic disorders

Identifiers

PMID29400443
PMCPMC5955820
OpenAlexW2785607982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.