ArticleHuman brain mapping2018
Brain structure differences between Chinese and Caucasian cohorts: A comprehensive morphometry study.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Magnetic Resonance Imaging and Its Clinical Correlation in Spinocerebellar Ataxia Type 3: A Systematic Review.Frontiers in neuroscience · 2022Pooled it
- Culture, prefrontal volume, and memory.PloS one · 2024Trial
- Volume-inflation registration (INFREG) for morphometric analysis of human focal cortical dysplasia type II.iScience · 2026Article
- Neurovariability as a signature of adaptive brain function.Brain structure & function · 2026Review
- Probabilistic maps of white matter hyperintensity in a Chinese aging cohort and application for clinical diagnosis.European radiology · 2026Article
- Atrial Fibrillation, Brain Structure and Cognitive Function: A Mediation Analysis.Korean circulation journal · 2026Article
- Charting brain morphology in international healthy and neurological populations.Nature neuroscience · 2026Article
- Effect of database, pre-processing pipeline, and scan duration on rs-fMRI functional connectivity based treatment targets for TMS obtained using the Stanford Neuromodulation Therapy (SNT) protocol.Psychoradiology · 2026Article
- Real-world federated learning for brain imaging scientists.Frontiers in digital health · 2026Article
- Early but discontinued exposure to a language exerts lasting effects on white matter architecture in the brain.Communications biology · 2025Article
- When Brain Models Aren't Universal: Benchmarking of Ethnic Bias in MRI-Based Cognitive Prediction Across Modalities.bioRxiv : the preprint server for biology · 2025Article
- Human development, inequality, and their associations with brain structure across 29 countries.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Automatic measurement and reference values setting of intracranial cerebrospinal fluid volume: a large-scale analysis of computed tomography images.Quantitative imaging in medicine and surgery · 2025Article
- Population-specific brain charts reveal Chinese-Western differences in neurodevelopmental trajectories.bioRxiv : the preprint server for biology · 2025Article
- Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD Consortium.bioRxiv : the preprint server for biology · 2025Article
- Gyral peak variations between HCP and CHCP: functional and structural implications.Brain structure & function · 2025Article
- The role of brain mechanisms in diabetic peripheral neuropathy: recent advances and comprehensive analysis.Frontiers in cellular neuroscience · 2025Review
- Sex Differences in Cortical Structural Alterations in Major Depressive Disorder With Suicidal Ideation.Depression and anxiety · 2025Article
- An MRI Study of Morphology, Asymmetry, and Sex Differences of Inferior Precentral Sulcus.Brain topography · 2024Article
- A diffusion MRI tractography atlas for concurrent white matter mapping across Eastern and Western populations.Scientific data · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Numerous behavioral observations and brain function studies have demonstrated that neurological differences exist between East Asians and Westerners. However, the extent to which these factors relate to differences in brain structure is still not clear. As the basis of brain functions, the anatomical differences in brain structure play a primary and critical role in the origination of functional and behavior differences. To investigate the underlying differences in brain structure between the two cultural/ethnic groups, we conducted a comparative study on education-matched right-handed young male adults (age = 22-29 years) from two cohorts, Han Chinese (n = 45) and Caucasians (n = 45), using high-dimensional structural magnetic resonance imaging (MRI) data. Using two well-validated imaging analysis techniques, surface-based morphometry (SBM) and voxel-based morphometry (VBM), we performed a comprehensive vertex-wise morphometric analysis of the brain structures between Chinese and Caucasian cohorts. We identified consistent significant between-group differences in cortical thickness, volume, and surface area in the frontal, temporal, parietal, occipital, and insular lobes as well as the cingulate cortices. The SBM analyses revealed that compared with Caucasians, the Chinese population showed larger cortical structures in the temporal and cingulate regions, and smaller structural measures in the frontal and parietal cortices. The VBM data of the same sample was well-aligned with the SBM findings. Our findings systematically revealed comprehensive brain structural differences between young male Chinese and Caucasians, and provided new neuroanatomical insights to the behavioral and functional distinctions in the two cultural/ethnic populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.