Evidence map›Paper›PMID 29400347›Full record

ArticleArchives of psychology (Chicago, Ill.)2017

Effects of early trauma on psychosis development in clinical high-risk individuals and stability of trauma assessment across studies: a review.

Samantha L Redman, Cheryl M Corcoran, David Kimhy, Dolores Malaspina

Open access · greenAbstract read
In one paragraph

Article in Archives of psychology (Chicago, Ill.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samantha L RedmanIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Cheryl M CorcoranIcahn School of Medicine at Mount Sinai, New York, New York, USA.
David KimhyIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Dolores MalaspinaIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Icahn School of Medicine at Mount Sinai · US

Funding

Hippocampal Inflammation as a Pathophysiology for PsychosisR01MH110418 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MALASPINA, DOLORES · 2017 to 2021
$3.8M
Thought disorder and social cognition in clinical risk states for schizophreniaR01MH107558 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI CORCORAN, CHERYL MARY · 2016 to 2020
$3.3M
NIMH NIH HHS R01 MH107558NIMH NIH HHS R01 MH110418
6 · The paper itself

Abstract

Early trauma (ET), though broadly and inconsistently defined, has been repeatedly linked to numerous psychological disturbances, including various developmental stages of psychotic disorders. The prodromal phase of psychosis highlights a unique and relevant population that provides insight into the critical periods of psychosis development. As such, a relatively recent research focus on individuals at clinical high risk (CHR) for psychosis reveals robust associations of early life trauma exposures with prodromal symptoms and function in these cohorts. While prevalence rates of ET in CHR cohorts remain consistently high, methodological measures of traumatic experiences vary across studies, presenting potential problems for reliability and validity of results. This review aims to 1) highlight the existing evidence identifying associations of ET, of multiple forms, with both symptom severity and transition rates to psychosis in CHR individuals, 2) present data on the variability among trauma assessments and its implications for conclusions about its relationship with clinical variables, 3) describe cognitive deficits common in CHR cohorts, including perceptual and neurocognitive impairments, and their neural correlates, that may modify the relationship of ET to symptoms, and 4) propose future directions for standardization of trauma assessment in CHR cohorts to better understand its clinical and cognitive correlates.

Indexed as

Clinical High RiskEarly TraumaPsychosisTrauma Assessment

Identifiers

PMID29400347
PMCPMC5791764
OpenAlexW2777686066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.