Evidence map›Paper›PMID 29399852›Full record

Trial reportBritish journal of clinical pharmacology2018

Effects of training physicians in electronic prescribing in the outpatient setting on clinical, learning and behavioural outcomes: a cluster randomized trial.

F van Stiphout, J E F Zwart-van Rijkom, J Versmissen, H Koffijberg, J E C M Aarts, I H van der Sijs, T van Gelder, R A de Man, C B Roes, A C G Egberts and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in British journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Environmental Impact and Provider Satisfaction Associated with ePrescriptions in Otolaryngology: A Quality Improvement Study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

F van StiphoutDepartment of Internal Medicine & Centre for Research and Development of Education, University Medical Centre Utrecht, The Netherlands.ORCID 0000-0001-5657-0166
J E F Zwart-van RijkomDepartment of Clinical Pharmacy, University Medical Centre Utrecht, The Netherlands.
J VersmissenDepartment of Internal Medicine, Erasmus Medical Centre Rotterdam, The Netherlands.ORCID 0000-0003-0674-7765
H KoffijbergDepartment of Health Technology Assessment, Julius Center, University Medical Centre Utrecht, The Netherlands.
J E C M AartsInstitute of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
I H van der SijsDepartment of Hospital Pharmacy, Erasmus Medical Centre Rotterdam, The Netherlands.
T van GelderDepartment of Internal Medicine, Erasmus Medical Centre Rotterdam, The Netherlands.ORCID 0000-0001-5980-6947
R A de ManDepartment of Gastroenterology and Hepatology, Erasmus Medical Centre Rotterdam, The Netherlands.
C B RoesDepartment of Biostatistics, Julius Center, University Medical Centre Utrecht, The Netherlands.
A C G EgbertsDepartment of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, The Netherlands.
E W M T Ter BraakDepartment of Internal Medicine & Centre for Research and Development of Education, University Medical Centre Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsElectronic prescribing systems may improve medication safety, but only when used appropriately. The effects of task analysis-based training on clinical, learning and behavioural outcomes were evaluated in the outpatient setting, compared with the usual educational approach.

methodsThis was a multicentre, cluster randomized trial [EDUCATional intervention for IT-mediated MEDication management (MEDUCATE trial)], with physicians as the unit of analysis. It took place in the outpatient clinics of two academic hospitals. Participants comprised specialists and residents (specialty trainees, in the UK) and their patients. Training took the form of a small-group session and an e-learning. The primary outcome was the proportion of medication discrepancies per physician, measured as discrepancies between medications registered by physicians in the electronic prescribing system and those reported by patients. Clinical consequences were estimated by the proportion of patients per physician with at least one missed drug-drug interaction with the potential for causing adverse drug events. A questionnaire assessed physicians' knowledge and skills.

resultsAmong 124 participating physicians, primary outcome data for 115 (93%) were available. A total of 1094 patients were included. A mean of 48% of registered medications per physician were discrepant with the medications that their patients reported in both groups (P = 0.14). Due to registration omissions, a mean of 4% of patients per physician had one or more missed drug-drug interactions with the potential to cause a clinically relevant adverse drug event in the intervention group, and 7% in controls (P = 0.11). The percentages of correct answers on the knowledge and skills test were higher in the intervention group (57%) compared with controls (51%; P = 0.01).

conclusionThe training equipped outpatient physicians with the knowledge and skills for appropriate use of electronic prescribing systems, but had no effect on medication discrepancies.

Indexed as

Ambulatory CareAttitude of Health PersonnelClinical CompetenceElectronic PrescribingHealth Knowledge, Attitudes, PracticeLearningMedical Order Entry SystemsPractice Patterns, Physicians'Academic Medical CentersAdultAgedDrug InteractionsEducation, Medical, ContinuingFemaleHumansInappropriate Prescribingadverse drug eventscontinuing educationelectronic prescribingmedical order entry systemspatient safetyphysicians

Identifiers

PMID29399852
PMCPMC5980599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.