Evidence map›Paper›PMID 29399658›Full record

ArticleJournal of drug abuse2017

Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders.

Cheng Ji

Open access · diamondAbstract read
In one paragraph

Article in Journal of drug abuse, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Cheng JiDepartment of Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA.
Keck Hospital of USC · US

Funding

Primary role of Golgi stress in anti-HIV drug and alcohol abuse-induced hepatotoxicityR01DA042632 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JI, CHENG · 2017 to 2021
$2.1M
Nanocapsules that decompose alcohol as antidotes for alcohol intoxication.R21AA023952 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JI, CHENG · 2015 to 2016
$417k
NIAAA NIH HHS R21 AA023952NIDA NIH HHS R01 DA042632
6 · The paper itself

Abstract

Antiviral drugs and alcohol abuse-induced organelle stresses have been linked to many disorders and the underlying molecular mechanisms are under intense investigations. This brief review communicates emerging evidence and research trends on how certain antivirals and alcohol affect ER-Golgi trafficking, which potentially impacts the function and integrity of the Golgi apparatus contributing to endoplasmic reticulum stress and cellular injury.

Indexed as

AIDSAlcohol abuseERGolgi apparatusHIVLiver disorders

Identifiers

PMID29399658
PMCPMC5791917
OpenAlexW2766243619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.