Evidence map›Paper›PMID 29399640›Full record

ArticleNPJ 2D materials and applications2017

Detection and Mapping of DNA Methylation with 2D Material Nanopores.

Hu Qiu, Aditya Sarathy, Klaus Schulten, Jean-Pierre Leburton

Abstract read
In one paragraph

Article in NPJ 2D materials and applications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Fabrication of MoSMicromachines · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Fabrication and Applications of Solid-State Nanopores.Sensors (Basel, Switzerland) · 2019
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hu QiuBeckman Institute for Advanced Science and Technology, University of Illinois, Urbana, Illinois 61801, United States.
Aditya SarathyBeckman Institute for Advanced Science and Technology, University of Illinois, Urbana, Illinois 61801, United States.
Klaus SchultenBeckman Institute for Advanced Science and Technology, University of Illinois, Urbana, Illinois 61801, United States.
Jean-Pierre LeburtonBeckman Institute for Advanced Science and Technology, University of Illinois, Urbana, Illinois 61801, United States.

Funding

WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TAJKHORSHID, EMAD · 2012 to 2021
$19.0M
NIGMS NIH HHS P41 GM104601
6 · The paper itself

Abstract

DNA methylation is an epigenetic modification involving the addition of a methyl group to DNA, which is heavily involved in gene expression and regulation, thereby critical to the progression of diseases such as cancer. In this work we show that detection and localization of DNA methylation can be achieved with nanopore sensors made of two-dimensional (2D) materials such as graphene and molybdenum di-sulphide (MoS

Indexed as

ionic currentmethylationmolecular dynamicsnanoporesheet current

Identifiers

PMID29399640
PMCPMC5794036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.