ArticleScience advances2018
In-air microfluidics enables rapid fabrication of emulsions, suspensions, and 3D modular (bio)materials.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 212 citations in OpenAlex.
- Autonomous and Communicative Microcapsule Systems for Life-Like Homeostatic pH Regulation.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Programmable Microcarriers for Stem Cell Therapy: Advanced Fabrication Strategies, Stem Cell Fate Regulatory Function and Biomedical Applications.International journal of molecular sciences · 2026Review
- Orthogonally crosslinked gelatin methacryloyl microgels for in situ assembly of granular hydrogel scaffolds.Bioengineering & translational medicine · 2026Article
- Surface Energy-Confined Multi-Layer Inkjet Printing for Customizable Optical Microstructures.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Frontier Technologies in Single-Cell Analysis: Synergistic Fusion of Droplet Printing and High-Performance Detection System.Analytical science advances · 2025Review
- Multiscale Structure-Property Relationships in Gelatin-Based Granular Hydrogel Scaffolds.ACS macro letters · 2025Article
- Extending the Range of Sizes of Monodisperse Core-Shell Hydrogel Capsules from Composite Jet Breakup by Combined Electrical and Mechanical Actuation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications.MedComm · 2025Review
- Microfluidics-Engineered Microcapsules: Advances in Thermal Energy Storage and Regulation.Micromachines · 2025Review
- Wetting-induced interfacial instability: A mechanism for droplet emission at air-liquid interfaces.Science advances · 2025Article
- Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration.Pharmaceutics · 2025Article
- Gene hydrogel platforms for targeted skin therapy: bridging hereditary disorders, chronic wounds, and immune related skin diseases.Frontiers in drug delivery · 2025Review
- Additive manufacturing of 3D flow-focusing millifluidics for the production of curable microdroplets.RSC advances · 2024Article
- Continuous Synthesis of Nanoscale Emulsions by Vapor Condensation (EVC).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Recent Progress in Droplet Structure Machining for Advanced Optics.Micromachines · 2024Review
- The microparticulate inks for bioprinting applications.Materials today. Bio · 2024Review
- Single-Step Biofabrication of In Situ Spheroid-Forming Compartmentalized Hydrogel for Clinical-Sized Cartilage Tissue Formation.Advanced healthcare materials · 2024Article
- Colloidal robotics.Nature materials · 2023Review
- Mass production of lumenogenic human embryoid bodies and functional cardiospheres using in-air-generated microcapsules.Nature communications · 2023Article
- Synthesis and Characterization of Carbon Microbeads.ACS omega · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microfluidic chips provide unparalleled control over droplets and jets, which have advanced all natural sciences. However, microfluidic applications could be vastly expanded by increasing the per-channel throughput and directly exploiting the output of chips for rapid additive manufacturing. We unlock these features with in-air microfluidics, a new chip-free platform to manipulate microscale liquid streams in the air. By controlling the composition and in-air impact of liquid microjets by surface tension-driven encapsulation, we fabricate monodisperse emulsions, particles, and fibers with diameters of 20 to 300 μm at rates that are 10 to 100 times higher than chip-based droplet microfluidics. Furthermore, in-air microfluidics uniquely enables module-based production of three-dimensional (3D) multiscale (bio)materials in one step because droplets are partially solidified in-flight and can immediately be printed onto a substrate. In-air microfluidics is cytocompatible, as demonstrated by additive manufacturing of 3D modular constructs with tailored microenvironments for multiple cell types. Its in-line control, high throughput and resolution, and cytocompatibility make in-air microfluidics a versatile platform technology for science, industry, and health care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.