Evidence map›Paper›PMID 29399611›Full record

ArticleEndoscopy international open2018

Multiple convex demarcation line for prediction of benign depressed gastric lesions in magnifying narrow-band imaging.

Takashi Kanesaka, Noriya Uedo, Kenshi Yao, Yasumasa Ezoe, Hisashi Doyama, Ichiro Oda, Kazuhiro Kaneko, Yoshiro Kawahara, Chizu Yokoi, Yasushi Sugiura and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endoscopy international open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 1 country.

Takashi KanesakaDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Noriya UedoDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Kenshi YaoDepartment of Endoscopy, Fukuoka University Chikushi Hospital, Fukuoka, Japan.
Yasumasa EzoeDepartment of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hisashi DoyamaDepartment of Gastroenterology, Ishikawa Prefectural Central Hospital, Ishikawa, Japan.
Ichiro OdaEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Kazuhiro KanekoDepartment of Gastroenterology, Endoscopy Division, National Cancer Center Hospital East, Chiba, Japan.
Yoshiro KawaharaDivision of Endoscopy, Okayama University, Okayama, Japan.
Chizu YokoiEndoscopy Division, National Center for Global Health and Medicine, Tokyo, Japan.
Yasushi SugiuraDivision of Gastroenterology and Hepatology, Kitano Hospital, Osaka, Japan.
Hideki IshikawaDepartment of Molecular Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yoji TakeuchiDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Masamichi AraoDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Taro IwatsuboDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Hiroyoshi IwagamiDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Kenji MatsunoDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Manabu MutoDepartment of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yutaka SaitoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Yasuhiko TomitaDepartment of Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan.
Osaka Medical Center for Cancer and Cardiovascular Diseases · JPNational Cancer Center Hospital East · JPKyoto University · JPFukuoka University · JPIshikawa Prefectural Central Hospital · JPKitano Hospital · JPKyoto Prefectural University of Medicine · JPNational Center for Global Health and Medicine · JPOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND STUDY

aimsWith magnifying narrow-band imaging (M-NBI) of the gastric mucosa, a characteristic demarcation line (DL) is occasionally found in non-cancerous depressed lesions. This DL forms multiple convex shapes along the edge of the epithelia of surrounding mucosa. We have termed this novel finding a multiple convex DL (MCDL). In this study, we clarified the prevalence of an MCDL in depressed gastric lesions detected in patients at high risk for gastric cancer and determined the diagnostic yield necessary to distinguish between cancer and non-cancer. PATIENTS AND

methodsThis was a

resultsImages of 347 lesions (39 cancerous and 308 non-cancerous) were evaluable. A DL was present in 252/347 lesions (73 %). When the cutoff value for the proportion of MCDLs needed to distinguish non-cancer from cancer was set at two-thirds, an MCDL was observed in 86/252 lesions (34 %). In 86 lesions with an MCDL, 83 (97 %) were non-cancerous. The sensitivity, specificity, positive predictive value, and negative predictive value of an MCDL for non-cancerous lesions were 38 %, 91 %, 97 %, and 19 %, respectively.

conclusionsPresence of an MCDL had high specificity and positive predictive value for non-cancerous lesions. Evaluating the shape of the DL is useful for differentiation between cancer and non-cancerous lesions.

Identifiers

PMID29399611
PMCPMC5794433
OpenAlexW2787219787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.