Evidence map›Paper›PMID 29399528›Full record

ReviewCardiovascular diagnosis and therapy2017

Anti-fouling strategies for central venous catheters.

Alex Wallace, Hassan Albadawi, Nikasha Patel, Ali Khademhosseini, Yu Shrike Zhang, Sailendra Naidu, Grace Knuttinen, Rahmi Oklu

Open access · hybridAbstract readReview
In one paragraph

Review in Cardiovascular diagnosis and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Prevention of uropathogenicRSC applied interfaces · 2024
    Article
  4. Article
  5. Review
  6. Biogenic silver nanoparticles (AgNPs) fromFrontiers in chemistry · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Alex WallaceDepartment of Radiology, Mayo Clinic, Phoenix, AZ, USA.
Hassan AlbadawiDivision of Vascular & Interventional Radiology, Mayo Clinic, Phoenix, AZ, USA.
Nikasha PatelDivision of Vascular & Interventional Radiology, Mayo Clinic, Phoenix, AZ, USA.
Ali KhademhosseiniDepartment of Bioengineering, Department of Chemical and Biomolecular Engineering, Henry Samueli School of Engineering and Applied Sciences, University of California-Los Angeles (UCLA), Los Angeles, CA, USA.
Yu Shrike ZhangDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, USA.
Sailendra NaiduDivision of Vascular & Interventional Radiology, Mayo Clinic, Phoenix, AZ, USA.
Grace KnuttinenDivision of Vascular & Interventional Radiology, Mayo Clinic, Phoenix, AZ, USA.
Rahmi OkluDivision of Vascular & Interventional Radiology, Mayo Clinic, Phoenix, AZ, USA.
Mayo Clinic in Florida · USHarvard University · USMayo Clinic Hospital · USUniversity of California, Los Angeles · US

Funding

Hemorrhage control in the irreversible anticoagulated patientR01HL137193 · NHLBI · MAYO CLINIC ARIZONA · PI OKLU, RAHMI · 2017 to 2021
$3.0M
Targeted chemotherapy delivery and captureR01EB024403 · NIBIB · MAYO CLINIC ARIZONA · PI KHADEMHOSSEINI, ALI, OKLU, RAHMI · 2017 to 2020
$2.2M
Catheter guided endovascular electric field ablation for thrombosis therapy.R21EB021148 · NIBIB · MAYO CLINIC ARIZONA · PI KHADEMHOSSEINI, ALI, OKLU, RAHMI · 2016 to 2017
$485k
Circulating tumor cells in hepatocellular carcinomaR03CA172738 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2013 to 2014
$171k
NCI NIH HHS R03 CA172738NHLBI NIH HHS R01 HL137193NIBIB NIH HHS R01 EB024403NIBIB NIH HHS R21 EB021148
6 · The paper itself

Abstract

Central venous catheters (CVCs) are ubiquitous in the healthcare industry and carry two common complications, catheter related infections and occlusion, particularly by thrombus. Catheter-related bloodstream infections (CRBSI) are an important cause of nosocomial infections that increase patient morbidity, mortality, and hospital cost. Innovative design strategies for intravenous catheters can help reduce these preventable infections. Antimicrobial coatings can play a major role in preventing disease. These coatings can be divided into two major categories: drug eluting and non-drug eluting. Much of these catheter designs are targeted at preventing the formation of microbial biofilms that make treatment of CRBSI nearly impossible without removal of the intravenous device. Exciting developments in catheter impregnation with antibiotics as well as nanoscale surface design promise innovative changes in the way that physicians manage intravenous catheters. Occlusion of a catheter renders the catheter unusable and is often treated by tissue plasminogen activator administration or replacement of the line. Prevention of this complication requires a thorough understanding of the mechanisms of platelet aggregation, signaling and cross-linking. This article will look at the advances in biomaterial design specifically drug eluting, non-drug eluting, lubricious coatings and micropatterning as well as some of the characteristics of each as they relate to CVCs.

Indexed as

Biofoulingcatheterscentral venous catheters (CVCs)infectionsthrombosis

Identifiers

PMID29399528
PMCPMC5778515
OpenAlexW2765151042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.