ReviewCardiovascular diagnosis and therapy2017
Can thrombus age guide thrombolytic therapy?
Review in Cardiovascular diagnosis and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 90 citations in OpenAlex.
- Molecular-gated MRIMaterials today. Bio · 2026Article
- Intravascular organizing thrombus in the forearm: a unique imaging presentation.Skeletal radiology · 2026Article
- Seeing the Unseen: Contrast-Free MRI for Predicting Thrombolytic Susceptibility.Circulation. Cardiovascular imaging · 2025Article
- Early percutaneous thrombolysis for AVF thrombosis: symptom duration as a predictor of endovascular salvage.CVIR endovascular · 2025Article
- Incidence of Unapparent Preoperative Deep Vein Thrombosis in Patients with Traumatic Intraarticular Tibial Plateau Fracture.Journal of clinical medicine · 2025Article
- Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Review
- Dual-layer dual-energy CT characterization of thrombus composition in acute pulmonary embolism and chronic thromboembolic pulmonary hypertension.The international journal of cardiovascular imaging · 2025Article
- Pathology of Self-Expanding Transcatheter Aortic Bioprostheses and Hypoattenuated Leaflet Thickening.Circulation. Cardiovascular interventions · 2025Article
- How well do 3D-printed tissue mimics represent the complex mechanics of biological soft tissues? An example study with Stratasys' cardiovascular TissueMatrix materials.Journal of biomedical materials research. Part A · 2025Article
- Neutrophil extracellular traps worsen clotting and neuroinflammation in cavernomas.Nature cardiovascular research · 2024Article
- Pharmacological blocking of neutrophil extracellular traps attenuates immunothrombosis and neuroinflammation in cerebral cavernous malformation.Nature cardiovascular research · 2024Article
- Evaluating the stage of deep vein thrombosis: the diagnostic accuracy of shear wave elastography and super-microvascular imaging.Quantitative imaging in medicine and surgery · 2024Article
- Predictors of Residual Pulmonary Vascular Obstruction after Acute Pulmonary Embolism Based on Patient Variables and Treatment Modality.Journal of clinical medicine · 2024Article
- Aging of deep venous thrombosisBiomedical optics express · 2024Article
- Mechanical thrombectomy of venous in-stent thrombosis with the novel RevCore thrombectomy system: A report of 2 cases.Radiology case reports · 2024Article
- Hypodense cerebral venous sinus thrombosis on unenhanced CT: Time-dependent change of CT attenuation in intravenous thrombus.Radiology case reports · 2024Article
- Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics.Methodist DeBakey cardiovascular journal · 2024Review
- Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Selective thrombolysis trans-catheter for safe and effective subacute stent graft occlusion treatment.Radiology case reports · 2023Article
- Ultrasound Elastography to Assess Age of Deep Vein Thrombosis: A Systematic Review.Diagnostics (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
Venous thrombosis (VT) is a common yet complex clinical condition that has shown minimal alteration in clinical management for decades. It is well known that thrombus evolves structurally over time, with complex changes resulting from the interplay between coagulation factors, cytokines, leukocytes and a myriad of other factors. Our current treatment options are most effective in the acute thrombus, which is composed predominantly of a loose mesh of fibrin and red blood cells (RBCs), making current anticoagulation therapies and thrombolytics quite effective in treatment. Later stages of thrombus are more cellular containing leukocytes, and develop a fibrotic collagenous framework that is more resistant to our current treatments. Understanding the biology of an evolving thrombus will allow us to tailor our treatment and optimize outcomes, as well as focus on novel therapies for the treatment of chronic thrombus. Given the morbidity and mortality of both post thrombotic syndrome (PTS) in patients with deep VT, as well as chronic thromboembolic pulmonary hypertension (CTEPH) in patients with pulmonary embolism (PE), new and innovative therapies must continue to be explored to help prevent these potentially devastating conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.