ArticleClinical psychological science : a journal of the Association for Psychological Science2017
Distinct patterns of reduced prefrontal and limbic grey matter volume in childhood general and internalizing psychopathology.
Article in Clinical psychological science : a journal of the Association for Psychological Science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- A Developmentally Informed Systematic Review and Meta-Analysis of the Strength of General Psychopathology in Childhood and Adolescence.Clinical child and family psychology review · 2024Pooled it
- Neural substrates of motivational dysfunction across neuropsychiatric conditions: Evidence from meta-analysis and lesion network mapping.Clinical psychology review · 2022Pooled it
- Application of a diathesis-stress model to the interplay of cortical structural development and emerging depression in youth.Clinical psychology review · 2020Pooled it
- Moving the dial on prenatal stress mechanisms of neurodevelopmental vulnerability to mental health problems: A personalized prevention proof of concept.Developmental psychobiology · 2021Trial
- An experimental test of the fetal programming hypothesis: Can we reduce child ontogenetic vulnerability to psychopathology by decreasing maternal depression?Development and psychopathology · 2018Trial
- Differential adolescent neurodevelopment of emotion processing across internalizing psychopathology and childhood adversity.Developmental cognitive neuroscience · 2026Article
- Distinct associations between multimodal brain measures and psychopathology domains predict adolescent functioning.bioRxiv : the preprint server for biology · 2026Article
- Alterations in resting-state functional connectivity relate to psychopathology trajectories during emerging adolescence.JCPP advances · 2026Article
- Neurostructural Substrates of Hierarchical Dimensions of Internalizing Symptoms in Youth.Human brain mapping · 2026Article
- Article
- Prospective Relations between Cortical Thickness and Change in Internalizing Symptoms are Moderated by Chronic Stress Exposure in Adolescents with Depression and Anxiety.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Hippocampal subregion volumes and preadolescent depression risk in the ABCD sample.Journal of affective disorders · 2025Article
- Can socioeconomic status moderate the effect of a conflictive family environment on brain structure and externalizing/internalizing behavior in children and adolescents?Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
- Impulsivity in ADHD and Borderline Personality Disorder: A Systematic Review of Gray and White Matter Variations.Journal of clinical medicine · 2024Review
- Smaller hippocampal volume is associated with anxiety symptoms in high-risk Black youth.Journal of mood and anxiety disorders · 2024Article
- Mapping potential pathways from polygenic liability through brain structure to psychological problems across the transition to adolescence.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- Right frontal cingulate cortex mediates the effect of prenatal complications on youth internalizing behaviors.Molecular psychiatry · 2024Article
- Stage 2 Registered Report: The Bidirectional Relationship Between Brain Features and the Dysregulation Profile: A Longitudinal, Multimodal Approach.Journal of the American Academy of Child and Adolescent Psychiatry · 2023Article
- Reduced volume of the left cerebellar lobule VIIb and its increased connectivity within the cerebellum predict more general psychopathology one year later via worse cognitive flexibility in children.Developmental cognitive neuroscience · 2023Article
- Sex and age variations in the impact of puberty on cortical thickness and associations with internalizing symptoms and suicidal ideation in early adolescence.Developmental cognitive neuroscience · 2023Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Reduced grey matter volume (GMV) is widely implicated in psychopathology, but studies have found mostly overlapping areas of GMV reduction across disorders rather than unique neural signatures, potentially due to pervasive comorbidity. GMV reductions may be associated with broader psychopathology dimensions rather than specific disorders. We used an empirically supported bifactor model consisting of common psychopathology and internalizing- and externalizing-specific factors to evaluate whether latent psychopathology dimensions yield a clearer, more parsimonious pattern of GMV reduction in prefrontal and limbic/paralimbic areas implicated in individual disorders. A community sample of children (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.