Evidence map›Paper›PMID 29399330›Full record

ReviewF1000Research2018

Recent advances in managing differentiated thyroid cancer.

Livia Lamartina, Giorgio Grani, Cosimo Durante, Sebastiano Filetti

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

  1. [A nomogram combining ultrasound radiomics and clinical features for predicting pathological invasiveness of papillary thyroid carcinoma].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
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  6. The role of miR-139-5p in radioiodine-resistant thyroid cancer.Journal of endocrinological investigation · 2023
    Article
  7. Review
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  14. Bioinformatic Analysis of the Effect of theBioMed research international · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Updates on the Management of Thyroid Cancer.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Livia LamartinaDipartimento di Medicina Interna e Specialità Mediche, Università di Roma "Sapienza", Viale del Policlinico 155, 00161 Rome, Italy.
Giorgio GraniDipartimento di Medicina Interna e Specialità Mediche, Università di Roma "Sapienza", Viale del Policlinico 155, 00161 Rome, Italy.
Cosimo DuranteDipartimento di Medicina Interna e Specialità Mediche, Università di Roma "Sapienza", Viale del Policlinico 155, 00161 Rome, Italy.
Sebastiano FilettiDipartimento di Medicina Interna e Specialità Mediche, Università di Roma "Sapienza", Viale del Policlinico 155, 00161 Rome, Italy.ORCID https://orcid.org/0000-0001-8570-6448
Policlinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main clinical challenge in the management of thyroid cancer is to avoid over-treatment and over-diagnosis in patients with lower-risk disease while promptly identifying those patients with more advanced or high-risk disease requiring aggressive treatment. In recent years, novel clinical and molecular data have emerged, allowing the development of new staging systems, predictive and prognostic tools, and treatment approaches. There has been a notable shift toward more conservative management of low- and intermediate-risk patients, characterized by less extensive surgery, more selective use of radioisotopes (for both diagnostic and therapeutic purposes), and less intensive follow-up. Furthermore, the histologic classification; tumor, node, and metastasis (TNM) staging; and American Thyroid Association risk stratification systems have been refined, and this has increased the number of patients in the low- and intermediate-risk categories. There is now a need for new, prospective data to clarify how these changing practices will impact long-term outcomes of patients with thyroid cancer, and new follow-up strategies and biomarkers are still under investigation. On the other hand, patients with more advanced or high-risk disease have a broader portfolio of options in terms of treatments and therapeutic agents, including multitarget tyrosine kinase inhibitors, more selective BRAF or MEK inhibitors, combination therapies, and immunotherapy.

Indexed as

radioisotopesThyroid cancerTMN staging

Identifiers

PMID29399330
PMCPMC5773927
OpenAlexW2784174721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.