ArticleJournal of innovative optical health sciences2017
3D Characterization of corneal deformation using ultrasound speckle tracking.
Article in Journal of innovative optical health sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Regional Biomechanical Weakening in Keratoconus Corneas Detected by In Vivo High-Frequency Ultrasound Elastography.Translational vision science & technology · 2025Article
- Three-Dimensional Ultrasound Elastography Detects Age-Related Increase in Anterior Peripapillary Sclera and Optic Nerve Head Compression During IOP Elevation.Investigative ophthalmology & visual science · 2023Article
- Method for the biomechanical analysis of aqueous veins and perilimbal sclera by three-dimensional photoacoustic imaging and strain field calculation.Scientific reports · 2021Article
- Regional variation of corneal stromal deformation measured by high-frequency ultrasound elastography.Experimental biology and medicine (Maywood, N.J.) · 2021Article
- IOP-induced regional displacements in the optic nerve head and correlation with peripapillary sclera thickness.Experimental eye research · 2020Article
- Corneal Hydration Control during Ex Vivo Experimentation Using Poloxamers.Current eye research · 2020Article
- Ocular Pulse Elastography: Imaging Corneal Biomechanical Responses to Simulated Ocular Pulse Using Ultrasound.Translational vision science & technology · 2020Article
- Mechanical Deformation of Human Optic Nerve Head and Peripapillary Tissue in Response to Acute IOP Elevation.Investigative ophthalmology & visual science · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The three-dimensional (3D) mechanical response of the cornea to intraocular pressure (IOP) elevation has not been previously reported. In this study, we use an ultrasound speckle tracking technique to measure the 3D displacements and strains within the central 5.5 mm of porcine corneas during the whole globe inflation. Inflation tests were performed on dextran-treated corneas (treated with a 10% dextran solution) and untreated corneas. The dextran-treated corneas showed an inflation response expected of a thin spherical shell, with through-thickness thinning and in-plane stretch, although the strain magnitudes exhibited a heterogeneous spatial distribution from the central to more peripheral cornea. The untreated eyes demonstrated a response consistent with swelling during experimentation, with through-thickness expansion overriding the inflation response. The average volume ratios obtained in both groups was near 1 confirming general incompressibility, but local regions of volume loss or expansion were observed. These results suggest that biomechanical measurements in 3D provide important new insight to understand the mechanical response of ocular tissues such as the cornea.
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Registered trials
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