Evidence map›Paper›PMID 29399055›Full record

ReviewTherapeutic advances in medical oncology2018

Refractory thyroid carcinoma: which systemic treatment to use?

Laurence Faugeras, Anne-Sophie Pirson, Julian Donckier, Luc Michel, Julien Lemaire, Sebastien Vandervorst, Lionel D'Hondt

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in medical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laurence FaugerasOncology Department, CHU UCL Namur, 1 rue Therasse, 5530 Yvoir, Belgium.
Anne-Sophie PirsonDepartment of Nuclear Medicine, CHU UCL Namur, Yvoir, Belgium.
Julian DonckierDepartment of Endocrinology, CHU UCL Namur, Yvoir, Belgium.
Luc MichelDepartment of General Surgery, CHU UCL Namur, Yvoir, Belgium.
Julien LemaireDepartment of General Surgery, CHU UCL Namur, Yvoir, Belgium.
Sebastien VandervorstENT Department, CHU UCL Namur, Yvoir, Belgium.
Lionel D'HondtOncology Department, CHU UCL Namur, Yvoir, Belgium.
CHU Dinant Godinne UCL Namur · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of thyroid cancer has increased markedly in recent decades, but has been stable in terms of mortality rates. For the most part, these cancers are treated with surgery, which may or may not be followed by radioactive iodine depending on the tumor subtype. Still, many of these cancers will recur and may be treated with radioactive iodine or another surgery. It is unclear what treatment is best for cases of locally advanced or metastatic thyroid cancer that are refractory to radioactive iodine. Chemotherapy has a very low response rate. However, in the past few years, several systemic therapies, primarily targeted, have emerged to improve the overall survival of these patients. Alternative treatments are also of interest, namely peptide receptor radionuclide therapy or immunotherapy.

Indexed as

chemotherapymutationspeptide receptor radionuclide therapyPRRTthyroid carcinomatyrosine kinase inhibitor

Identifiers

PMID29399055
PMCPMC5788129
OpenAlexW2792712116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.