ArticleTherapeutic advances in gastroenterology2018
The Lewis score or the capsule endoscopy Crohn's disease activity index: which one is better for the assessment of small bowel inflammation in established Crohn's disease?
Article in Therapeutic advances in gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Pooled it
- Characterization of Mucosal Lesions in Crohn's Disease Scored With Capsule Endoscopy: A Systematic Review.Frontiers in medicine · 2020Pooled it
- Small bowel capsule endoscopy and treat-to-target in Crohn's disease: A systematic review.World journal of gastroenterology · 2019Pooled it
- A novel PillCam Crohn's capsule score (Eliakim score) for quantification of mucosal inflammation in Crohn's disease.United European gastroenterology journal · 2020Trial
- Protective Effects of Natural Products, Functional Foods, and Probiotics on NSAID-Induced Small Intestinal Injury: A Systematic Review with Mechanistic Considerations of Oxidative Stress and Microbiome Modulation.Antioxidants (Basel, Switzerland) · 2026Review
- Capsule Endoscopy in Inflammatory Bowel Disease: Current Status and Issues in Clinical Practice.DEN open · 2026Review
- Pan-enteric Capsule Endoscopy in Crohn's Disease: Impact on Therapeutic Decisions and Inter-observer Agreement in a Multicentre Case-based Study.Endoscopy international open · 2026Article
- Article
- Small Bowel Capsule Endoscopy and Enteroscopy: A Shoulder-to-Shoulder Race.Journal of clinical medicine · 2023Review
- Reclassification of Inflammatory Bowel Disease Type Unclassified by Small Bowel Capsule Endoscopy.Medicina (Kaunas, Lithuania) · 2023Article
- Is Panenteric PillcamDiagnostics (Basel, Switzerland) · 2023Review
- Mucosal Healing and Clinical Efficacy of Adalimumab in Small Intestinal Crohn's Disease (SIMCHA Study): Final Results From a Prospective, Open-Label, Single-Arm Study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Video Capsule Endoscopy Plays an Important Role in the Management of Crohn's Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Video capsule endoscopy in inflammatory bowel disease.DEN open · 2022Review
- Magnetically Guided Capsule Endoscopy and Magnetic Resonance Enterography in Children With Crohn's Disease: Manifestations and the Value of Assessing Disease Activity.Frontiers in pharmacology · 2022Article
- Capsule Endoscopy Is Useful for Postoperative Tight Control Management in Patients with Crohn's Disease.Digestive diseases and sciences · 2022Article
- Capsule Endoscopy in Inflammatory Bowel Disease: When? To Whom?Diagnostics (Basel, Switzerland) · 2021Review
- Assessment of a new score for capsule endoscopy in pediatric Crohn's disease (CE-CD).Endoscopy international open · 2021Article
- Capsule Endoscopy in Crohn's Disease-From a Relative Contraindication to Habitual Monitoring Tool.Diagnostics (Basel, Switzerland) · 2021Review
- Crohn's Disease Only Visible on Small Bowel Capsule Endoscopy: A New Entity.Digestive diseases and sciences · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSmall-bowel capsule endoscopy (CE) is a prime modality for evaluation of the small bowel. The Lewis score (LS) and the Capsule Endoscopy Crohn's Disease Activity Index (CECDAI) are validated endoscopic indices for quantification of small-bowel inflammation on CE. It is unclear whether these indexes are interchangeable for the evaluation of mucosal inflammation in established Crohn's disease (CD). The aim of this study was to compare the quantitative evaluation of small- bowel inflammation by LS and CECDAI.
methodsPatients with known quiescent small-bowel CD for at least 3 months (Crohn's disease activity index < 150) were prospectively recruited and underwent CE. The LS was calculated using RAPID 8 capsule-reading software and the CECDAI was calculated manually. Cumulative LS (C-LS) was calculated by summation of individual tertile LS. Fecal calprotectin (FCP) and C-reactive protein (CRP) levels were measured and correlated with the scores.
resultsA total of 50 patients were included in the study. There was a moderate correlation between the worst segment LS and CECDAI (Pearson's
conclusionsCECDAI and C-LS are strongly correlated and perform similarly for quantitative assessment of mucosal inflammation in established CD.
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