SynthesisWorld journal of gastroenterology2018
Impact of mechanical bowel preparation in elective colorectal surgery: A meta-analysis.
Synthesis in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 6 syntheses or guidelines pooled it, 170 citations in OpenAlex.
- Risk and protective factors for postoperative anastomotic leakage in esophageal and gastrointestinal surgery: an umbrella review of meta-analyses and systematic reviews.International journal of surgery (London, England) · 2026Pooled it
- The effect of preoperative mechanical bowel preparation in paediatric bowel surgery on postoperative wound related complications: A meta-analysis.International wound journal · 2024Pooled it
- Antibiotic prophylaxis in colorectal surgery: are oral, intravenous or both best and is mechanical bowel preparation necessary?Techniques in coloproctology · 2020Pooled it
- A comparison between limited bowel preparation and comprehensive bowel preparation in radical cystectomy with ileal urinary diversion: a systematic review and meta-analysis of randomized controlled trials.International urology and nephrology · 2020Pooled it
- The Role of Oral Antibiotic Preparation in Elective Colorectal Surgery: A Meta-analysis.Annals of surgery · 2019Pooled it
- The value of mechanical bowel preparation prior to pediatric colorectal surgery: a systematic review and meta-analysis.Pediatric surgery international · 2018Pooled it
- Trial
- Impact of Postoperative Infectious Complications on Long-Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era.Annals of gastroenterological surgery · 2026Article
- Preoperative stool scale is a risk factor for anastomotic leakage after minimally invasive low anterior resection for rectal cancer.Surgery today · 2026Article
- Adaptation of Enhanced Recovery After Surgery Protocol for Elective Gastrointestinal and Hepatopancreaticobiliary Surgeries for Tertiary Hospitals in Ethiopia: A Modified Delphi Study.World journal of surgery · 2026Article
- Effect of mechanical bowel preparation with antibiotics and probiotics on postoperative ileus in patients undergoing posterior lumbar spine surgeries: a randomized controlled trial.Asian spine journal · 2026Article
- Application of enhanced recovery after surgery in laparoscopic biliary reoperation for extrahepatic bile duct stones.Frontiers in surgery · 2026Article
- Anastomotic Leak Following Colorectal Surgery.Clinics in colon and rectal surgery · 2026Review
- Application of enhanced recovery after surgery in perioperative care of infants and children with Hirschsprung disease.World journal of gastrointestinal surgery · 2025Article
- The implementation of complex infection control bundles to prevent colorectal surgical site infections: a survey of SHEA research network hospitals.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Article
- [Anastomotic leaks in colorectal surgery].Chirurgie (Heidelberg, Germany) · 2024Article
- Bowel preparation for elective colorectal resection: multi-treatment machine learning analysis on 6241 cases from a prospective Italian cohort.International journal of colorectal disease · 2024Article
- The Impact of Mechanical Bowel Preparation and Oral Antibiotics in Colorectal Cancer Surgery (MECCA Study): A Prospective Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Perioperative Fluid Management in Colorectal Surgery: Institutional Approach to Standardized Practice.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
aimTo analyse the effect of mechanical bowel preparation
methodsMeta-analysis of randomised controlled trials and observational studies comparing adult patients receiving mechanical bowel preparation with those receiving no mechanical bowel preparation, subdivided into those receiving a single rectal enema and those who received no preparation at all prior to elective colorectal surgery.
resultsA total of 36 studies (23 randomised controlled trials and 13 observational studies) including 21568 patients undergoing elective colorectal surgery were included. When all studies were considered, mechanical bowel preparation was not associated with any significant difference in anastomotic leak rates (OR = 0.90, 95%CI: 0.74 to 1.10,
conclusionIn the most comprehensive meta-analysis of mechanical bowel preparation in elective colorectal surgery to date, this study has suggested that the use of mechanical bowel preparation does not affect the incidence of postoperative complications when compared with no preparation. Hence, mechanical bowel preparation should not be administered routinely prior to elective colorectal surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.