ArticleEuropean journal of plastic surgery2018
A new treatment of hypertrophic and keloid scars with combined triamcinolone and verapamil: a retrospective study.
Article in European journal of plastic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Therapeutic methods and effect on keloid and hypertrophic scars: a systematic review.Frontiers in medicine · 2026Pooled it
- Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2023Pooled it
- Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial.International wound journal · 2023Trial
- Comparison of Effectiveness of Intralesional Triamcinolone Acetonide with Fractional CO2 Laser Against Intralesional Triamcinolone Acetonide with Intralesional Verapamil in the Treatment of Keloids.Indian dermatology online journal · 2025Article
- Leveraging Microneedles for Raised Scar Management.Polymers · 2025Review
- Losartan in Situ Forming Gel as a New Treatment for Hypertrophic Scars.Aesthetic plastic surgery · 2025Article
- Comprehensive Insights into Keloid Pathogenesis and Advanced Therapeutic Strategies.International journal of molecular sciences · 2024Review
- Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents.Archives of dermatological research · 2023Review
- Progress in the clinical treatment of keloids.Frontiers in medicine · 2023Review
- Vacuum and Electromagnetic Fields Treatment to Regenerate a Diffuse Mature Facial Scar Caused by Sulfuric Acid Assault.Bioengineering (Basel, Switzerland) · 2022Article
- 180-W GreenLight laser photoselective vaporization with multiple triamcinolone acetonide injections for the treatment of bladder neck contractures.Lasers in medical science · 2022Article
- Treatment of Keloids: A Meta-analysis of Intralesional Triamcinolone, Verapamil, and Their Combination.Plastic and reconstructive surgery. Global open · 2022Article
- Facial Scars Due to Prone Position Pressure Ulcers: Underestimated Sequelae in COVID-19 Survivors?Aesthetic surgery journal · 2021Article
- Article
- A six-herb Chinese medicine composition ointment as a promising candidate for treatment of hypertrophic scars.Chinese herbal medicines · 2021Article
- Management of highly recurrent bladder neck contractures via transurethral resection combined with intra- and post-operative triamcinolone acetonide injections.World journal of urology · 2021Article
- Emerging and Novel Therapies for Keloids: A compendious review.Sultan Qaboos University medical journal · 2021Review
- Direct Delivery of Apatite Nanoparticle-Encapsulated siRNA Targeting TIMP-1 for Intractable Abnormal Scars.Molecular therapy. Nucleic acids · 2020Article
- The Role of IL-6 in Skin Fibrosis and Cutaneous Wound Healing.Biomedicines · 2020Review
- Integrated Interaction Network of MicroRNA Target Genes in Keloid Scarring.Molecular diagnosis & therapy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince the management of keloid and hypertrophic scars still remains a difficult clinical problem, there is need for adequate, effective therapy. In this study, we explored for the first time the efficacy and the potential synergetic effect of combined triamcinolone and verapamil for the treatment of hypertrophic and keloid scars. The objective was to assess the efficacy of combined intralesional triamcinolone and verapamil therapy for hypertrophic and keloid scars.
methodsFifty-eight patients with hypertrophic scars (
resultsOur results reveal a fast and abiding improvement of both keloid and hypertrophic scars after treatment with the combination therapy. All POSAS components showed a reduction in scar score, while scar relief, pain, itchiness, and surface area improved significantly (
conclusionsThis study reveals that combined therapy of triamcinolone and verapamil results in overall significant scar improvement with a long-term stable result.Level of evidence: Level IV, therapeutic study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.