ArticleJournal of atherosclerosis and thrombosis2018
Screening Validity of Arterial Pressure-Volume Index and Arterial Velocity-Pulse Index for Preclinical Atherosclerosis in Japanese Community-Dwelling Adults: the Nagasaki Islands Study.
Article in Journal of atherosclerosis and thrombosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Effects of high-intensity interval training on improving arterial stiffness in Chinese female university students with normal weight obese: a pilot randomized controlled trial.Journal of translational medicine · 2022Trial
- Multidomain Arterial Afterload and Left Atrial-Left Ventricular Coupling in Hypertensive Phenotypes.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Association of Echocardiographic Ventricular-Arterial Coupling With Elevated 10-Year ASCVD Risk in Hypertensive Patients.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Moving the Goalposts in Hypertensive Risk Assessment: The AVI/LVGLS Ratio as a Sensitive Detector of Maladaptive Ventricular-Arterial Coupling.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Unraveling Changes of Brachial Artery Residual Stress and Its Relationship to Cardiovascular Disease Risk Factors.Reviews in cardiovascular medicine · 2024Article
- A Novel Index System for Assessing Ventricular-Vascular Coupling.Reviews in cardiovascular medicine · 2023Article
- Increased arterial pressure volume index and cardiovascular risk score in China.BMC cardiovascular disorders · 2023Article
- Association of Arterial Stiffness Indices with Framingham Cardiovascular Disease Risk Score.Reviews in cardiovascular medicine · 2022Article
- Relationships Between Arterial Pressure-Volume Index and Cardiovascular Disease Biomarkers in Patients With Hypertension.Journal of clinical medicine research · 2022Article
- New indices of arterial stiffness correlate with disease severity and mid-term prognosis in acute decompensated heart failure.Internal and emergency medicine · 2021Observational
- Increased arterial velocity pulse index is an independent factor related to skeletal muscle mass reduction and tissue damage in patients with cardiovascular disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Clinical Significance of Arterial Velocity Pulse Index in Patients With Stage B Heart Failure With Preserved Ejection Fraction.Cardiology research · 2019Article
- Noninvasive Assessment of Arterial Stiffness Using Oscillometric Methods: baPWV, CAVI, API, and AVI.Journal of atherosclerosis and thrombosis · 2018Article
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9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe arterial pressure-volume index (API) and arterial velocity-pulse index (AVI) are novel measurement indices of arterial stiffness. This study was performed to examine the screening validity of the API and AVI for preclinical atherosclerosis in Japanese community-dwelling adults.
methodsWe conducted a cross-sectional study of 2,809 participants aged ≥40 years who underwent Japanese national medical check-ups from 2014 to 2016. Preclinical atherosclerosis was defined as a mean carotid intima-media thickness (CIMT) of ≥1.0 mm. Multivariable linear regression analysis was performed to investigate the association of CIMT with API and AVI, adjusting for body mass index, sex, and the Framingham-D'Agostino score. We also examined receiver operating characteristic curves, sensitivity, and specificity to predict preclinical atherosclerosis defined by the CIMT. The cardio-ankle vascular index was also measured for comparison with the API and AVI.
resultsOf 2,809 participants, 68 (2.4%) had preclinical atherosclerosis. In the multivariable linear regression analysis, the API and AVI maintained a positive association with the mean CIMT (B=2.6, P=0.009 and B=3.7, P=0.001, respectively). The cut-offs of the API and AVI that demonstrated better sensitivity and specificity for detection of subclinical atherosclerosis were 31 [area under the curve (AUC), 0.64] and 29 (AUC, 0.60).
conclusionsThe API and AVI were positively associated with preclinical carotid atherosclerosis independent of the participants' cardiovascular risk. The ability of these scores to predict carotid atherosclerosis could make them a useful screening tool for atherosclerosis.
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